Exploratory Study on the Timing of Multiple Sclerosis (MS) Symptoms

NCT00919217 | Terminated DMC

• 1 other identifier: 08.0172
• Study Type: observational
• Target: 80
• Locations: 1 country
• Sites: 1

Brief Summary

The investigators' overall hypothesis is that appearance or worsening of relapsing-remitting multiple sclerosis (RR-MS) symptoms are affected by various factors including stress, hormonal cycles, illness and missed medications.

Conditions

Relapsing Remitting Multiple Sclerosis

Keywords

Multiple Sclerosis; MS; Relapsing-remitting multiple sclerosis; RR-MS; Women

Outcome Measures

Primary Outcomes (1)

• number of days with appearance or worsening of symptoms

  3 months

Secondary Outcomes (1)

• timing of appearance or worsening of symptoms

  3 months

Study Arms (1)

Relapsing-remitting multiple sclerosis

Females with relapsing-remitting multiple sclerosis

Eligibility Criteria

• Age: 18 Years - 50 Years
• Sex: female
• Healthy Volunteers: No
• Age Groups: Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

Females with relapsing-remitting multiple sclerosis, not menopausal, neither pregnant nor nursing, not treated with steroids in the last 30 days and not on experimental medications

You may qualify if:

• females
• diagnosed with relapsing-remitting multiple sclerosis

You may not qualify if:

• male
• no diagnosis of relapsing-remitting MS
• diagnosis of any other autoimmune disease or fibromyalgia
• peri-, post-, or surgically menopausal
• pregnant within past year or nursing
• history of chemotherapy
• on experimental medications
• treatment with steroids in the last 30 days

Sponsors & Collaborators

• University of Louisville: lead

Study Sites (1)

University of Louisville (recruiting nationwide)

Louisville, Kentucky, 40292, United States

Location

MeSH Terms

Conditions

Multiple Sclerosis, Relapsing-Remitting; Multiple Sclerosis

Condition Hierarchy (Ancestors)

Demyelinating Autoimmune Diseases, CNS; Autoimmune Diseases of the Nervous System; Nervous System Diseases; Demyelinating Diseases; Autoimmune Diseases; Immune System Diseases

Study Officials

• Cynthia Corbitt, PhD

  University of Louisville, Dept. Biology

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associate Professor

Study Record Dates

• First Submitted: June 10, 2009
• First Posted: June 12, 2009
• Study Start: August 1, 2008
• Primary Completion: May 1, 2025
• Study Completion: May 1, 2025
• Last Updated: April 15, 2026

Record last verified: 2026-04

Locations

US (1)