NCT00918918|CompletedDMC
Effect of Alcohol Consumption on Markers of Inflammation
AR23
The Effect of Moderate Alcohol Consumption on a Human in Vivo Model of Low-grade Systemic Inflammation in Young, Normal-weight Men
Loading search results
AR23
The Effect of Moderate Alcohol Consumption on a Human in Vivo Model of Low-grade Systemic Inflammation in Young, Normal-weight Men
Sponsor study identifier
interventional
24
1 country
1
Study Start
August 2009
Date type not reportedThis date has not been verified as actual or estimated.
Primary Completion
November 2009
Actual (reported)Study Completion
November 2009
Actual (reported)Rationale: High-density lipoprotein (HDL), which is consistently increased after moderate alcohol consumption, is an abundant plasma lipoprotein that is generally thought to be anti-inflammatory in both health and infectious disease. HDL binds and neutralizes the bioactivity of potent bacterial remnants such as lipopolysaccharides (LPS) which stimulate the host innate immune responses. Primary objective: To explore whether prolonged moderate alcohol consumption affects in vivo cytokine response after a low dose of LPS in young, normal-weight men.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
November 2009
Actual (reported)Click on a node to explore related trials.
Some registry-reported names shown below are not yet linked in this graph.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
June 10, 2009
Actual (reported)June 11, 2009
Actual (reported)August 2009
Date type not reportedThis date has not been verified as actual or estimated.
November 2009
Actual (reported)November 2009
Actual (reported)In vivo cytokine response after low-dose LPS challenge
December 2009
de novo adiponectin protein synthesis
December 2010
changes in microbiota
December 2010
Vodka + orange juice
Orange juice
100 mL Vodka (37.5 vol%; 30 gram of alcohol/day) + 200 mL orange juice
200 mL orange juice
Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.
TNO Quality of Life
Zeist, 3704HE, Netherlands
Joosten MM, Schrieks IC, Hendriks HF. Effect of moderate alcohol consumption on fetuin-A levels in men and women: post-hoc analyses of three open-label randomized crossover trials. Diabetol Metab Syndr. 2014 Feb 18;6(1):24. doi: 10.1186/1758-5996-6-24.
Henk FJ Hendriks, PhD
TNO
24 participants (actual enrollment reported by the registry).
First Submitted
June 10, 2009
First Posted
June 11, 2009
Study Start
August 2009
Date type not reportedThis date has not been verified as actual or estimated.
Effect of Alcohol on Cephalic Phase Reflex and Gene Expression
Contact the study team to confirm eligibility.
Primary Completion
November 2009
Actual (reported)Study Completion
November 2009
Actual (reported)Last Updated
November 25, 2009
Record last verified: 2009-11
Download the complete ClinicalTrials.gov record imported by Syfrah, including fields not shown in this page. The registry may contain a newer revision.
Source: ClinicalTrials.gov.
JSON downloads include source attribution and retrieval details alongside the unchanged original record or the separately normalized values.
Source retrieved: