NCT00917670

Brief Summary

Ultrastructural analysis of trabeculectomy specimens of patients with uveitic secondary glaucoma. To evaluate morphological changes and to compare to primary open angle glaucoma patients.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
10

participants targeted

Target at below P25 for all trials

Timeline
Completed

Started May 2009

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

May 1, 2009

Completed
1 month until next milestone

First Submitted

Initial submission to the registry

June 9, 2009

Completed
1 day until next milestone

First Posted

Study publicly available on registry

June 10, 2009

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 1, 2009

Completed
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2009

Completed
Last Updated

July 22, 2010

Status Verified

July 1, 2010

Enrollment Period

4 months

First QC Date

June 9, 2009

Last Update Submit

July 21, 2010

Conditions

UveitisSecondary Glaucoma

Keywords

trabecular meshworkelectron microscopy

Outcome Measures

Primary Outcomes (1)

  • morphological changes

    after surgery

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Patients with uveitic secondary glaucoma in need of surgical intervention.

You may qualify if:

  • secondary uveitic glaucoma
  • IOP \> 24 mmhg with topical and/or systemic therapy
  • need for surgical intervention to control IOP

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Department of Anatomy II at University of Erlangen, Germany

Erlangen, Germany

Location

Related Links

Biospecimen

Retention: SAMPLES WITH DNA

trabeculectomy specimens including trabecular meshwork and Schlemms canal

MeSH Terms

Conditions

Uveitis

Condition Hierarchy (Ancestors)

Uveal DiseasesEye Diseases

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER

Study Record Dates

First Submitted

June 9, 2009

First Posted

June 10, 2009

Study Start

May 1, 2009

Primary Completion

September 1, 2009

Study Completion

December 1, 2009

Last Updated

July 22, 2010

Record last verified: 2010-07

Locations

DE(1)