Multisystemic Therapy to Reduce Health Disparities in Adolescents With Asthma
2 other identifiers
interventional
170
1 country
1
Brief Summary
Asthma is a chronic lung disease that inflames and narrows the airways. Symptoms can include recurring periods of wheezing, chest tightness, shortness of breath, and coughing. Minority, inner city teens are at increased risk for complications from the disease, possibly because of poor illness management. The purpose of this study is to test the effectiveness of Multisystemic Therapy (MST)-an intensive, home- and community-based psychotherapy-for improving asthma management and overall health and for reducing healthcare costs for inner city African American teens with asthma.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for not_applicable asthma
Started Sep 2008
Longer than P75 for not_applicable asthma
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
September 1, 2008
CompletedFirst Submitted
Initial submission to the registry
June 5, 2009
CompletedFirst Posted
Study publicly available on registry
June 9, 2009
CompletedPrimary Completion
Last participant's last visit for primary outcome
June 1, 2013
CompletedStudy Completion
Last participant's last visit for all outcomes
June 1, 2013
CompletedAugust 19, 2016
July 1, 2009
4.8 years
June 5, 2009
August 18, 2016
Conditions
Keywords
Outcome Measures
Primary Outcomes (2)
Pulmonary functioning (FEV-1, FVC)
Measured at study entry and Months 7 (post treatment) and 12
Hospital and emergency department utilization (for asthma exacerbation)
Measured at study entry and Months 7 (post treatment) and 12
Secondary Outcomes (1)
Identification of mediators and moderators of MST treatment effects, e.g., individual adolescent factors (asthma knowledge/skill, mental health); family factors (family routines and relationships), etc.
Measured at study entry and Months 7 (post treatment) and 12
Study Arms (2)
1
EXPERIMENTALParticipants will receive Multisystemic Therapy (MST).
2
ACTIVE COMPARATORParticipants will receive home-based, non-directive family support.
Interventions
Treatment will consist of a home- and community-based intensive intervention. Psychological treatment sessions will be provided in participants' homes, at a time designated by the participant and will last about 1 hour.
Treatment will consist of Rogerian, client-centered, non-directive counseling. Participants will receive weekly home-based, supportive family counseling, with sessions lasting about 45 minutes.
Eligibility Criteria
You may qualify if:
- Moderate to severe persistent asthma
- African American
- One or more hospitalizations for asthma in the last 12 months
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Wayne State University School of Medicine
Detroit, Michigan, 48201, United States
Related Publications (1)
Naar S, Ellis D, Cunningham P, Pennar AL, Lam P, Brownstein NC, Bruzzese JM. Comprehensive Community-Based Intervention and Asthma Outcomes in African American Adolescents. Pediatrics. 2018 Oct;142(4):e20173737. doi: 10.1542/peds.2017-3737. Epub 2018 Sep 5.
PMID: 30185428DERIVED
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Sylvie Naar-King, PhD
Wayne State University
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- SINGLE
- Who Masked
- OUTCOMES ASSESSOR
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- NIH
Study Record Dates
First Submitted
June 5, 2009
First Posted
June 9, 2009
Study Start
September 1, 2008
Primary Completion
June 1, 2013
Study Completion
June 1, 2013
Last Updated
August 19, 2016
Record last verified: 2009-07