Intensive Care Unit (ICU) Admission Decisions in the Elderly : the ICE-CUB Study
IceCub
A Prospective Multicenter Study Examining the Criteria That Determine ICU Admission of Patients Over 80 Who Present to an Emergency Department and Evaluating the Impact of ICU Admission on Short and Mid-term Vital and Functional Outcome
1 other identifier
observational
2,643
1 country
1
Brief Summary
Percentage of patients over 80 admitted in ICU varies greatly from one center to another. ICU admission criteria of older patients are scarcely described and benefit of ICU admission for those patients is uncertain. In this study, we prospectively studied old patients arriving to the emergency department of 15 French hospitals with conditions that potentially warrant ICU admission.The working hypothesis was that ICU admission was associated with a 20% decrease in six-month mortality.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Nov 2004
Longer than P75 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
November 1, 2004
CompletedPrimary Completion
Last participant's last visit for primary outcome
January 1, 2006
CompletedStudy Completion
Last participant's last visit for all outcomes
February 1, 2009
CompletedFirst Submitted
Initial submission to the registry
June 2, 2009
CompletedFirst Posted
Study publicly available on registry
June 3, 2009
CompletedJuly 26, 2012
May 1, 2009
1.2 years
June 2, 2009
July 25, 2012
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
ICU eligibility as assessed by emergency and ICU physicians
At the admission
Secondary Outcomes (3)
Hospital death
During the hospitalisation
Change in functional status
During 6 months
Six-month death
During 6 months after the end of the hospitalisation
Study Arms (1)
1
Elderly individuals presenting to one of 15 emergency departments and possibly qualifying for admission to an ICU
Interventions
Eligibility Criteria
Old patients arriving to the emergency department of 15 French hospitals with conditions that potentially warrant ICU admission.
You may qualify if:
- Age over 80
- Be assigned by the emergency physician with one of 74 conditions potentially warranting ICU admission
You may not qualify if:
- Patient's refusal
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Hôpital Saint-Antoine
Paris, 75012, France
Related Publications (1)
Boumendil A, Angus DC, Guitonneau AL, Menn AM, Ginsburg C, Takun K, Davido A, Masmoudi R, Doumenc B, Pateron D, Garrouste-Orgeas M, Somme D, Simon T, Aegerter P, Guidet B; ICE-CUB study group. Variability of intensive care admission decisions for the very elderly. PLoS One. 2012;7(4):e34387. doi: 10.1371/journal.pone.0034387. Epub 2012 Apr 11.
PMID: 22509296DERIVED
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Bertrand GUIDET, MD
Assistance Publique - Hôpitaux de Paris
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
June 2, 2009
First Posted
June 3, 2009
Study Start
November 1, 2004
Primary Completion
January 1, 2006
Study Completion
February 1, 2009
Last Updated
July 26, 2012
Record last verified: 2009-05