NCT00911417

Brief Summary

The Jetstream System is a commercially available rotating, aspirating, expandable catheter designed to remove atherosclerotic plaque and blood clots in the lower limbs. The purpose of this study is to use intravascular ultrasound (IVUS) during the interventional procedure to measure the amount of plaque and blood clots removed by the Jetstream System.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
40

participants targeted

Target at P25-P50 for phase_4

Timeline
Completed

Started Jun 2009

Typical duration for phase_4

Geographic Reach
1 country

5 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

May 19, 2009

Completed
13 days until next milestone

First Posted

Study publicly available on registry

June 1, 2009

Completed
Same day until next milestone

Study Start

First participant enrolled

June 1, 2009

Completed
2.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 1, 2011

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

August 1, 2011

Completed
Last Updated

September 5, 2011

Status Verified

September 1, 2011

Enrollment Period

2.1 years

First QC Date

May 19, 2009

Last Update Submit

September 2, 2011

Conditions

Keywords

peripheral arterial diseaseperipheral vascular disease

Outcome Measures

Primary Outcomes (1)

  • Plaque Morphology

    up to 12 month follow-up

Interventions

The Pathway Jetstream System is a commercially available rotating, aspirating, expandable catheter for active removal of plaque and blood clots in peripheral arteries of the lower limbs.

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • The patient is ≥ 18 years of age.
  • The documented peripheral vascular disease is/are located in a superficial femoral, popliteal or tibial peroneal trunk arteries in the lower limb.
  • The patient is an acceptable candidate for percutaneous intervention using the Jetstream G2 System in accordance with its labeled indications and instructions for use.
  • The patient has been informed about the nature of the study and has provided informed consent.

You may not qualify if:

  • Patient has no distal runoff.
  • Interventional treatment is intended for in-stent restenosis at the peripheral vascular site.
  • Patient is pregnant or nursing a child.
  • Intended interventional treatment includes planned laser, brachytherapy or atherectomy procedure other than the Jetstream G2 System.
  • Patient has clinically significant abnormal ECG or blood test results or any other factor that would put the patient at increased risk if participating in the study.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (5)

Arizona Heart Institute

Phoenix, Arizona, 85006, United States

Location

St. Luke's Hospital

Phoenix, Arizona, 85006, United States

Location

St. John's Hospital

Springfield, Illinois, 62701, United States

Location

St. John Hospital & Medical Ctr.

Detroit, Michigan, 48236, United States

Location

Mount Sinai Medical Center

New York, New York, 10029, United States

Location

MeSH Terms

Conditions

Peripheral Arterial DiseasePeripheral Vascular Diseases

Condition Hierarchy (Ancestors)

AtherosclerosisArteriosclerosisArterial Occlusive DiseasesVascular DiseasesCardiovascular Diseases

Study Officials

  • Tom Davis, MD

    St. John's Hospital and Medical Center

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
phase 4
Allocation
NON RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

May 19, 2009

First Posted

June 1, 2009

Study Start

June 1, 2009

Primary Completion

July 1, 2011

Study Completion

August 1, 2011

Last Updated

September 5, 2011

Record last verified: 2011-09

Locations