NCT00908895

Brief Summary

The treatment of extra-articular distal radius fractures is still controversial. In Canada, most patients with unstable fractures are treated with pinning and cast. Results are often associated with shortening and lack of function. The purpose of the study is to compare stabilization with a radio-radial fixator to the usual method, suggesting that the radio-radial fixator will provide more strength at 6 months follow-up.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
120

participants targeted

Target at P25-P50 for phase_3

Timeline
Completed

Started Apr 2003

Typical duration for phase_3

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

April 1, 2003

Completed
4.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 1, 2007

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

May 1, 2007

Completed
2.1 years until next milestone

First Submitted

Initial submission to the registry

May 26, 2009

Completed
1 day until next milestone

First Posted

Study publicly available on registry

May 27, 2009

Completed
1 year until next milestone

Results Posted

Study results publicly available

June 7, 2010

Completed
Last Updated

March 1, 2011

Status Verified

November 1, 2009

Enrollment Period

4.1 years

First QC Date

May 26, 2009

Results QC Date

November 12, 2009

Last Update Submit

February 25, 2011

Conditions

Keywords

Radius fracturesRadio-radial fixatorPercutaneous pinningGrip strength

Outcome Measures

Primary Outcomes (1)

  • The Grip Strength

    Grip strength measured with Jamar dynamometer in kilograms and adjusted to the opposite side in percentage. Correction made according to dominance.

    6 months

Secondary Outcomes (1)

  • Range of Movement of Wrist

    6 months

Study Arms (2)

Radio-radial fixator

EXPERIMENTAL

Patients are operated on using a radio-radial fixator (Distal radius fixator, Synthes)

Procedure: Radio-radial fixator

Percutaneous pinning

ACTIVE COMPARATOR

Two K-wires inserted on a percutaneous way (dorsally and from the styloid), with a cast for 6 weeks

Procedure: Percutaneous pinning

Interventions

Using the Distal Radius Fixator from Synthes. A single splint for 5 days.

Radio-radial fixator

Insert two K-wires in the distal radius, one in the fracture line dorsally and one from the styloid. A cast for 6 weeks.

Percutaneous pinning

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Distal radius fracture Frykman I or II
  • Unstable fracture according to Lafontaine's criteria
  • Fracture line more than 1cm form the joint line
  • Closed fracture
  • Age \> 18 years
  • Surgery performed between 72 hours from the trauma
  • Monotrauma
  • Patient signed the informed consent

You may not qualify if:

  • Distal radius fracture Frykman III-VI (intra-articular fracture)
  • Open fracture
  • Polytraumatism
  • Stable or non-displaced fracture

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Département d'orthopédie, CHA-Pavillon Enfant-Jésus

Québec, Quebec, G1J1Z4, Canada

Location

MeSH Terms

Conditions

Radius Fractures

Condition Hierarchy (Ancestors)

Forearm InjuriesArm InjuriesWounds and InjuriesFractures, Bone

Limitations and Caveats

Very long time between the end of the study and the manuscript preparation due to temporarily lack of statistician and the need for some national associations that the study is not published before presentation.

Results Point of Contact

Title
Dr Stéphane Pelet, MD, PhD
Organization
Département d'orthopédie, CHA-Pavillon Enfant-Jésus Québec

Publication Agreements

PI is Sponsor Employee
No
Restrictive Agreement
No

Study Design

Study Type
interventional
Phase
phase 3
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER

Study Record Dates

First Submitted

May 26, 2009

First Posted

May 27, 2009

Study Start

April 1, 2003

Primary Completion

May 1, 2007

Study Completion

May 1, 2007

Last Updated

March 1, 2011

Results First Posted

June 7, 2010

Record last verified: 2009-11

Locations