NCT00903240

Brief Summary

The purpose of this study is to detect recurrent bladder cancer using a combination of protein and DNA biomarkers in urine

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
1,000

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started May 2009

Geographic Reach
1 country

20 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

May 1, 2009

Completed
13 days until next milestone

First Submitted

Initial submission to the registry

May 14, 2009

Completed
4 days until next milestone

First Posted

Study publicly available on registry

May 18, 2009

Completed
11 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 1, 2010

Completed
6 months until next milestone

Study Completion

Last participant's last visit for all outcomes

October 1, 2010

Completed
Last Updated

June 8, 2011

Status Verified

November 1, 2009

Enrollment Period

11 months

First QC Date

May 14, 2009

Last Update Submit

June 7, 2011

Conditions

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

The study population will be from urology and oncology practices

You may qualify if:

  • Intact bladder
  • Scheduled for cystoscopy for transitional cell bladder cancer recurrence screening
  • Urine donated prior to cystoscopy, Bladder biopsy, chemotherapy, intravesical therapy, radiation or TUR
  • Must be willing to sign IRB approved informed consent

You may not qualify if:

  • History or current diagnosis of any cancer except transitional cell bladder cancer or basal cell cancer
  • Known diagnosis of any autoimmune disease or HIV, HCV or HBV
  • History or current TB or any other active infection
  • Subject has gross hematuria
  • Receiving chemotherapy, intravesical therapy or radiation within 30 days of enrollment
  • Any surgery except urologic within past 30 days

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (20)

BCG Oncology

Phoenix, Arizona, 85032, United States

Location

Urology Associates

Engelwood, Colorado, 80113, United States

Location

Atlantic Urological Associates

Daytona Beach, Florida, 32114, United States

Location

Winter Park Urology

Orlando, Florida, 32803, United States

Location

Metropolitan Urology

Jeffersonville, Indiana, 47130, United States

Location

Mayo Validation Support Services

Rochester, Minnesota, 55901, United States

Location

Metro Urology

Woodbury, Minnesota, 55125, United States

Location

Associates in Urology/Urology Group of NJ

741 Northfield Avenue, New Jersey, 07052, United States

Location

Coastal Urology Associates

Brick, New Jersey, 08723, United States

Location

Capital Regional Urological Surgeons

Albany, New York, 12208, United States

Location

Community Care Physicians

Albany, New York, 12208, United States

Location

University Urology Associates

New York, New York, 10016, United States

Location

Hudson Valley Urology

Poughkeepsie, New York, 12601, United States

Location

Associated Medical Professionals

Syracuse, New York, 13210, United States

Location

The Urology Group

Cincinnati, Ohio, 45212, United States

Location

Urological Associates of Lancaster

Lancaster, Pennsylvania, 17601, United States

Location

Triangle Urologic Group

Pittsburgh, Pennsylvania, 15212, United States

Location

Carolina Urologic Research Center

Myrtle Beach, South Carolina, 29572, United States

Location

Urology Clinics of North Texas

Dallas, Texas, 75231, United States

Location

Urology San Antonio Research

San Antonio, Texas, 78229, United States

Location

Biospecimen

Retention: SAMPLES WITH DNA

The specimens to be retained are urine only

Study Officials

  • Ellen Sheets, MD

    Predictive Biosciences

    STUDY DIRECTOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
INDUSTRY

Study Record Dates

First Submitted

May 14, 2009

First Posted

May 18, 2009

Study Start

May 1, 2009

Primary Completion

April 1, 2010

Study Completion

October 1, 2010

Last Updated

June 8, 2011

Record last verified: 2009-11

Locations