Exercise Pulseoximetry for Pre-flight Evaluation of Chronic Obstructive Pulmonary Disease (COPD) Patients

NCT00896584 | Completed

• 4 other identifiers: GK-40/3S-08640b (REK)2541 (Biobank)2008/2/0079 (HelseRehab)
• Study Type: observational
• Target: 100
• Locations: 1 country
• Sites: 1

Brief Summary

Some patients with chronic obstructive pulmonary disease (COPD) need supplementary oxygen during air travel. Guidelines issued by The British Thoracic Society (BTS) for pre-flight evaluation do not discriminate sufficiently between those who need supplementary oxygen during flight, and those who can do without. Previous studies have indicated that decreasing hemoglobin oxygen saturation during exercise may predict in-flight hypoxemia. The objective of the present study is to examine if adding exercise oxygen desaturation to the BTS algorithm will better predict requirements for in-flight supplementary oxygen.

Conditions

Chronic Obstructive Pulmonary Disease; Hypoxemia

Keywords

Chronic obstructive pulmonary disease; Hypoxemia; Pre-flight evaluation; Hypobaria; COPD; Pulseoximetry; Air travel; Exercise desaturation

Eligibility Criteria

• Age: 40 Years - 80 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

COPD patients

You may qualify if:

• patients with COPD who have performed a hypoxia altitude simulation test
• able to perform the 6-minute walking test

You may not qualify if:

• unstable angina
• uncontrolled hypertension
• uncontrolled arrythmia
• patients with long-term oxygen treatment

Sponsors & Collaborators

• LHL Helse: lead

Study Sites (1)

Glittreklinikken

Hakadal, Hakadal, 1485, Norway

Location

Related Publications (4)

• Akero A, Christensen CC, Edvardsen A, Ryg M, Skjonsberg OH. Pulse oximetry in the preflight evaluation of patients with chronic obstructive pulmonary disease. Aviat Space Environ Med. 2008 May;79(5):518-24. doi: 10.3357/asem.2120.2008.

  PMID: 18500050 BACKGROUND

• Akero A, Christensen CC, Edvardsen A, Skjonsberg OH. Hypoxaemia in chronic obstructive pulmonary disease patients during a commercial flight. Eur Respir J. 2005 Apr;25(4):725-30. doi: 10.1183/09031936.05.00093104.

  PMID: 15802350 BACKGROUND

• British Thoracic Society Standards of Care Committee. Managing passengers with respiratory disease planning air travel: British Thoracic Society recommendations. Thorax. 2002 Apr;57(4):289-304. doi: 10.1136/thorax.57.4.289. No abstract available.

  PMID: 11923546 BACKGROUND

• Edvardsen A, Ryg M, Akero A, Christensen CC, Skjonsberg OH. COPD and air travel: does hypoxia-altitude simulation testing predict in-flight respiratory symptoms? Eur Respir J. 2013 Nov;42(5):1216-23. doi: 10.1183/09031936.00157112. Epub 2012 Dec 20.

  PMID: 23258777 DERIVED

MeSH Terms

Conditions

Pulmonary Disease, Chronic Obstructive; Hypoxia

Condition Hierarchy (Ancestors)

Lung Diseases, Obstructive; Lung Diseases; Respiratory Tract Diseases; Chronic Disease; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Signs and Symptoms, Respiratory; Signs and Symptoms

Study Officials

• Anne Edvardsen, MSc

  LHL Helse

  PRINCIPAL INVESTIGATOR

• Morten S Ryg, Dr philos

  LHL Helse

  STUDY DIRECTOR

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER

Study Record Dates

• First Submitted: May 8, 2009
• First Posted: May 11, 2009
• Study Start: May 1, 2009
• Primary Completion: November 1, 2010
• Study Completion: November 1, 2010
• Last Updated: November 18, 2010

Record last verified: 2010-11

Locations

NO (1)