Trends in Risk Factors for Mother-to-Child Transmission of Hepatitis C Among a Southern European Population

NCT00894257 | Completed

• 1 other identifier: 07-PP-06
• Study Type: observational
• Target: 142
• Locations: 1 country
• Sites: 3

Brief Summary

According to the centres taking part in the ALHICE survey, the number of HIV-HCV co-infected women is currently decreasing. This drop was first noted in 2006 and persisted in 2007. What might have been considered a chance phenomenon during the first year (2006) was confirmed in the beginning of 2008. In view of this information, the investigators wished to ascertain the reality of this trend and to investigate its causes, by attempting to answer the following questions: - Has the prevalence of risk factors for HCV infection changed among the general population over the past 10 years?

• Has the prevalence of risk factors for HCV infection changed among HIV/HCV co-infected women over the past 10 years?
• Is the change in the number of co-infected women who gave birth during the past 10 years related to the prevalence of certain risk factors among this population?
• Is the change in the number of co-infected women who gave birth during the past 10 years related to a decrease in certain risk factors for HCV infection among the general population?
• Have changes in addictive behaviour among women of child-bearing age played a role in the decreasing number of HCV-contaminated children? Furthermore, follow-up data from HCV-infected children born during this period will provide information concerning the course of HCV infection. The objectives are to study trends in numbers of deliveries among HCV/HIV co-infected women as well as trends in risk factors for HCV infection among women of child bearing age and lastly to create a cohort of HCV infected children.

Conditions

Hepatitis C Virus; HIV Infections; Pregnancy

Keywords

HCV infected pregnant women

Study Arms (1)

HCV/HIV infected pregnant women

Eligibility Criteria

• Age: 15 Years - 55 Years
• Sex: female
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

HCV/HIV infected pregnant women

You may qualify if:

• Infected HIV/HCV pregnant women
• All women to give birth in 1 randomized week each 6 months

Sponsors & Collaborators

• Centre Hospitalier Universitaire de Nice: lead

Study Sites (3)

CHU Montpellier

Montpellier, 34000, France

Location

CHU Nice

Nice, 06000, France

Location

CHU Toulouse

Toulouse, 31000, France

Location

MeSH Terms

Conditions

Hepatitis C; HIV Infections

Condition Hierarchy (Ancestors)

Blood-Borne Infections; Communicable Diseases; Infections; Hepatitis, Viral, Human; Virus Diseases; Flaviviridae Infections; RNA Virus Infections; Hepatitis; Liver Diseases; Digestive System Diseases; Sexually Transmitted Diseases, Viral; Sexually Transmitted Diseases; Lentivirus Infections; Retroviridae Infections; Genital Diseases; Urogenital Diseases; Immunologic Deficiency Syndromes; Immune System Diseases

Study Officials

• Eugénia MARINE-BARJOAN, MD

  Centre Hospitalier Universitaire de Nice

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER

Study Record Dates

• First Submitted: May 5, 2009
• First Posted: May 6, 2009
• Study Start: May 25, 2009
• Primary Completion: April 15, 2014
• Study Completion: April 15, 2014
• Last Updated: November 13, 2023

Record last verified: 2023-11

Locations

FR (3)