Comparison of Two Chest Radiograph Prescription Strategies in Intensive Care Unit
RARE
A Cluster-Randomized Two-Period Cross-Over Study Comparing Routine and on-Demand Prescription of Chest Radiographs in Mechanically Ventilated Adults : the RARE Study
1 other identifier
observational
849
1 country
1
Brief Summary
Current guidelines recommend Routine daily chest radiographs (CXRs) for mechanically ventilated patients in intensive care units (ICUs). However, some ICUs have shifted to an On-demand strategy, in which this CXR is only prescribed if warranted by the patient's status at the morning physical examination. Here the investigators compared Routine and On-demand strategies in 21 French ICUs. The working hypothesis was that CXR prescriptions would fall by at least 20% with the On-demand strategy, with no reduction in quality of care.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Dec 2006
Typical duration for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
December 1, 2006
CompletedPrimary Completion
Last participant's last visit for primary outcome
August 1, 2007
CompletedStudy Completion
Last participant's last visit for all outcomes
April 1, 2009
CompletedFirst Submitted
Initial submission to the registry
May 5, 2009
CompletedFirst Posted
Study publicly available on registry
May 6, 2009
CompletedMay 6, 2009
May 1, 2009
8 months
May 5, 2009
May 5, 2009
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Average number of chest radiographs per patient-day during mechanical ventilation
Every patient-day during mechanical ventilation.
Secondary Outcomes (4)
Mortality rate in ICU
During the inpatient stay in ICU
Average length of stay
During the inpatient stay in ICU
Average duration of mechanical ventilation
During the inpatient stay in ICU
Number of radiographs with new findings leading to therapeutic or diagnostic interventions
During the inpatient stay in ICU
Study Arms (2)
1
Routine strategy of chest radiograph prescription
2
On-demand strategy of chest radiograph prescription
Eligibility Criteria
All newly admitted adult patients receiving mechanical ventilation at the time of the morning visit in ICU
You may qualify if:
- All newly admitted adult patients receiving mechanical ventilation at the time of the morning visit-any day during their ICU stay
You may not qualify if:
- Patients with mechanical ventilation lasting less than 2 days
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Hopital Saint-Antoine
Paris, Paris, 75012, France
Related Publications (1)
Hejblum G, Chalumeau-Lemoine L, Ioos V, Boelle PY, Salomon L, Simon T, Vibert JF, Guidet B. Comparison of routine and on-demand prescription of chest radiographs in mechanically ventilated adults: a multicentre, cluster-randomised, two-period crossover study. Lancet. 2009 Nov 14;374(9702):1687-93. doi: 10.1016/S0140-6736(09)61459-8. Epub 2009 Nov 4.
PMID: 19896184DERIVED
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Bertrand GUIDET, MD PhD
Assistance Publique - Hôpitaux de Paris
Study Design
- Study Type
- observational
- Observational Model
- CASE CROSSOVER
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
Study Record Dates
First Submitted
May 5, 2009
First Posted
May 6, 2009
Study Start
December 1, 2006
Primary Completion
August 1, 2007
Study Completion
April 1, 2009
Last Updated
May 6, 2009
Record last verified: 2009-05