Treadmill Training and Quality of Life in Parkinson's Disease

NCT00890669 | Completed

• 2 other identifiers: 234/07CEP/UFSCar
• Study Type: interventional
• Target: 9
• Locations: 1 country
• Sites: 1

Brief Summary

Parkinson's disease (PD) causes motor and non-motor impairments that affect the quality of life of the subjects. The purpose was to assess the effects of treadmill walking training with additional body load on the quality of life and motor symptoms of the subjects with PD. Methods: Nine subjects with PD, Hoehn and Yahr stages 2 through 3, not demented and with capability to ambulate independently voluntarily participate in this study. The training program was divided into three phases (A1-B-A2): treadmill training with additional body load (A1), control condition (conventional physical therapy group) (B) and treadmill training with load again (A2). Each phase lasted six weeks. The quality of life and motor symptoms were assessed by PDQ-39 and UPDRS, respectively. Both evaluations and training were performed during on-phase of the medication cycle.

Conditions

Parkinson's Disease

Keywords

treadmill training; body load; quality of life; Parkinson's disease; Motor Symptoms

Outcome Measures

Primary Outcomes (1)

• The quality of life was measured through Parkinson Disease Questionnaire (PDQ-39).

  4 times, once before treatment, and 3 after each treatment phase.

Study Arms (1)

PD Group

EXPERIMENTAL

Nine subjects with idiopathic PD, previously diagnosed by one specialist physician participated in this study.

Other: Treadmill walking training with additional body load

Interventions

Treadmill walking training with additional body load OTHER

The training program was divided into three phases (A1-B-A2): * treadmill training with additional body load (A1), * control condition (conventional physical therapy group) (B). and * treadmill training with additional body load again (A2). Each phase lasted six weeks, totaling 18 weeks. Both evaluations and training were performed during on-phase of the medication cycle.

PD Group

Eligibility Criteria

• Age: 51 Years - 81 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Hoehn and Yahr (H-Y) stages 2 through 3
• Absence of dementia (Mini-Mental Status Examination - MMSE, defined according to educational level)
• Capacity to ambulate independently for at least 10 meters

You may not qualify if:

• Change medication (dopaminergic) during the study period
• Use treadmill for at least six months prior to the study
• Other neurologic problems or musculoskeletal, cardiovascular and respiratory disease or uncorrected visual deficit that could represent risk and interfere in the accomplishment of the training

Sponsors & Collaborators

• Universidade Federal de Sao Carlos: lead

Study Sites (1)

Universidade Federal de São Carlos

São Carlos, São Paulo, 13565-905, Brazil

Location

MeSH Terms

Conditions

Parkinson Disease

Condition Hierarchy (Ancestors)

Parkinsonian Disorders; Basal Ganglia Diseases; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Movement Disorders; Synucleinopathies; Neurodegenerative Diseases

Study Officials

• Nadiesca T Filippin, MSc

  Universidade Federal de Sao Carlos

  PRINCIPAL INVESTIGATOR

• Rosana Mattioli, PhD

  Universidade Federal de Sao Carlos

  STUDY CHAIR

• Paula H Lobo da Costa, PhD

  Universidade Federal de Sao Carlos

  STUDY DIRECTOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER

Study Record Dates

• First Submitted: April 28, 2009
• First Posted: April 30, 2009
• Study Start: August 1, 2007
• Study Completion: December 1, 2008
• Last Updated: May 4, 2009

Record last verified: 2009-05

Locations

BR (1)