NCT00881283

Brief Summary

The purpose of this study is to determine whether subjects who have been affected by Cushing's disease in the past maintain some different characteristics compared with subjects who have never been diagnosed with the disease.

Trial Health

57
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
1

participants targeted

Target at below P25 for all trials

Timeline
Completed

Started Sep 2008

Geographic Reach
1 country

1 active site

Status
terminated

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

September 8, 2008

Completed
7 months until next milestone

First Submitted

Initial submission to the registry

April 13, 2009

Completed
2 days until next milestone

First Posted

Study publicly available on registry

April 15, 2009

Completed
12 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 30, 2010

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

March 30, 2010

Completed
Last Updated

September 2, 2020

Status Verified

August 1, 2020

Enrollment Period

1.6 years

First QC Date

April 13, 2009

Last Update Submit

August 31, 2020

Conditions

Cushing's Disease

Keywords

Cushing's disease

Outcome Measures

Primary Outcomes (1)

  • adipokine measurements

    baseline

Study Arms (1)

cured Cushing's disease

Eligibility Criteria

Age35 Years - 55 Years
Sexfemale
Healthy VolunteersNo
Age GroupsAdult (18-64)
Sampling MethodProbability Sample
Study Population

Cured Cushing's disease

You may qualify if:

  • patients who have been cured of Cushing's disease at least 5 years ago.

You may not qualify if:

  • patients who have been cured of Cushing's disease more than 15 years ago.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Neuroendocrine Clinical Center

Boston, Massachusetts, 02114, United States

Location

Biospecimen

Retention: SAMPLES WITH DNA

serum, urine

MeSH Terms

Conditions

Pituitary ACTH Hypersecretion

Condition Hierarchy (Ancestors)

HyperpituitarismPituitary DiseasesHypothalamic DiseasesBrain DiseasesCentral Nervous System DiseasesNervous System DiseasesEndocrine System Diseases

Study Officials

  • Anne Klibanski, MD

    Massachusetts General Hospital

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
CASE CONTROL
Time Perspective
CROSS SECTIONAL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Chief, Neuroendocrine Unit

Study Record Dates

First Submitted

April 13, 2009

First Posted

April 15, 2009

Study Start

September 8, 2008

Primary Completion

March 30, 2010

Study Completion

March 30, 2010

Last Updated

September 2, 2020

Record last verified: 2020-08

Locations

US(1)