NCT00877786

Brief Summary

Cognitive Behavioral Therapy for Bulimia Nervosa (CBT4BN) is a research program funded by the National Institute of Mental Health and conducted by the UNC Eating Disorders Program and the University of Pittsburgh Medical Center. Cognitive Behavioral Therapy (CBT) is an evidence-based treatment and the gold-standard for treating bulimia nervosa. The current study aims to compare two forms of CBT: face-to-face group therapy and online group therapy via cbt4bn.org.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
196

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Apr 2008

Longer than P75 for not_applicable

Geographic Reach
1 country

2 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

April 1, 2008

Completed
1 year until next milestone

First Submitted

Initial submission to the registry

April 6, 2009

Completed
2 days until next milestone

First Posted

Study publicly available on registry

April 8, 2009

Completed
7.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 1, 2016

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

May 1, 2016

Completed
Last Updated

March 29, 2018

Status Verified

March 1, 2018

Enrollment Period

8.1 years

First QC Date

April 6, 2009

Last Update Submit

March 26, 2018

Conditions

Bulimia Nervosa

Outcome Measures

Primary Outcomes (1)

  • Abstinence from binge/purge episodes

    12 months

Secondary Outcomes (2)

  • Reduction of binge/purge episodes

    12 months

  • Maintenance of behavior change

    12 months

Study Arms (2)

Face-to-face group therapy

ACTIVE COMPARATOR
Behavioral: Cognitive Behavioral Group Therapy

Online chat group therapy

ACTIVE COMPARATOR
Behavioral: Cognitive Behavioral Group Therapy

Interventions

Cognitive Behavioral Group TherapyBEHAVIORAL

Cognitive behavioral therapy (CBT) is a form of psychotherapy that addresses the links between thoughts, emotions and behaviors.

Also known as: CBT, Cognitive Behavioral Therapy
Face-to-face group therapyOnline chat group therapy

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • DSM-IV criteria for BN
  • Internet access at home
  • Either off psychotropic medication for at least one month or on a stable dose of psychotropic medication

You may not qualify if:

  • Any major medical condition that would interfere with treatment or require alternative treatment
  • Alcohol or drug dependence in the last three months
  • Current significant suicidal ideation
  • Developmental disability that would impair the ability to use the internet program effectively
  • Psychosis, including schizophrenia, or bipolar I disorder

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

University of North Carolina at Chapel Hill

Chapel Hill, North Carolina, 27510, United States

Location

University of Pittsburgh

Pittsburgh, Pennsylvania, 15213, United States

Location

Related Publications (2)

  • Watson HJ, McLagan N, Zerwas SC, Crosby RD, Levine MD, Runfola CD, Peat CM, Moessner M, Zimmer B, Hofmeier SM, Hamer RM, Marcus MD, Bulik CM, Crow SJ. Cost-Effectiveness of Internet-Based Cognitive-Behavioral Treatment for Bulimia Nervosa: Results of a Randomized Controlled Trial. J Clin Psychiatry. 2018 Jan/Feb;79(1):16m11314. doi: 10.4088/JCP.16m11314.

    PMID: 29228517DERIVED

  • Levinson CA, Zerwas S, Calebs B, Forbush K, Kordy H, Watson H, Hofmeier S, Levine M, Crosby RD, Peat C, Runfola CD, Zimmer B, Moesner M, Marcus MD, Bulik CM. The core symptoms of bulimia nervosa, anxiety, and depression: A network analysis. J Abnorm Psychol. 2017 Apr;126(3):340-354. doi: 10.1037/abn0000254. Epub 2017 Mar 9.

    PMID: 28277735DERIVED

MeSH Terms

Conditions

Bulimia Nervosa

Interventions

Cognitive Behavioral Therapy

Condition Hierarchy (Ancestors)

Feeding and Eating DisordersMental Disorders

Intervention Hierarchy (Ancestors)

Behavior TherapyPsychotherapyBehavioral Disciplines and Activities

Study Officials

  • Cynthia Bulik, PhD

    University of North Carolina, Chapel Hill

    PRINCIPAL INVESTIGATOR

  • Marsha Marcus, PhD

    University of Pittsburgh

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Distinguished Professor of Eating Disorders

Study Record Dates

First Submitted

April 6, 2009

First Posted

April 8, 2009

Study Start

April 1, 2008

Primary Completion

May 1, 2016

Study Completion

May 1, 2016

Last Updated

March 29, 2018

Record last verified: 2018-03

Locations

US(2)