Prize Reinforcement Contingency Management for Cocaine Dependence: a 24-week Randomized Controlled Trial
1 other identifier
interventional
60
1 country
2
Brief Summary
The purpose of this study is to determine whether prize-based contingency management (prizeCM) combined with cognitive behavioral therapy (CBT) is more effective in the treatment of of cocaine-dependent patients compared to CBT only. Patients were randomized to prizeCM + CBT (experimental group) or to CBT (control group) an treated over 24 weeks. It is the first trial of this type in Europe.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for not_applicable
Started Sep 2008
Longer than P75 for not_applicable
2 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
September 1, 2008
CompletedFirst Submitted
Initial submission to the registry
April 6, 2009
CompletedFirst Posted
Study publicly available on registry
April 7, 2009
CompletedPrimary Completion
Last participant's last visit for primary outcome
August 1, 2013
CompletedStudy Completion
Last participant's last visit for all outcomes
October 1, 2014
CompletedJanuary 29, 2015
January 1, 2015
4.9 years
April 6, 2009
January 28, 2015
Conditions
Outcome Measures
Primary Outcomes (1)
retention in treatment, cocaine abstinence
cocaine abstinence: at least 3 consecutive weeks of cocaine abstinence, the maximum number of weeks of continous abstinence and proportions of cocaine-free urine samples during the entire 24-week and at 6-month follow-up.
24 weeks
Secondary Outcomes (1)
patients' satisfaction with the therapy, clinical measures
24 weeks
Study Arms (2)
1
EXPERIMENTALCognitive behavioral therapy (CBT) + prize-based contingency management (prizeCM)
2
ACTIVE COMPARATORCognitive behavioral therapy (CBT)
Interventions
Eligibility Criteria
You may qualify if:
- cocaine dependence, aged 18 or older, other dependences
You may not qualify if:
- severe somatic, brain, or psychiatric disease, attention deficit disorders with medication methylphenidate
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (2)
Universitäre Psychiatrischen Kliniken
Basel, 4025, Switzerland
Fondation Phenix
Geneva, 1221, Switzerland
Related Links
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Sylvie A Petitjean, Dr. phil.
Psychiatric Hospital of the University of Basel
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- SINGLE
- Who Masked
- PARTICIPANT
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Dr. phil
Study Record Dates
First Submitted
April 6, 2009
First Posted
April 7, 2009
Study Start
September 1, 2008
Primary Completion
August 1, 2013
Study Completion
October 1, 2014
Last Updated
January 29, 2015
Record last verified: 2015-01