Effectiveness Repetitive Transcranial Magnetic Stimulation (rTMS) in Patients With Chronic Tinnitus
Effectiveness of Combined Frontal and Temporal Repetitive Transcranial Magnetic Stimulation (rTMS) in Patients With Chronic Tinnitus
1 other identifier
interventional
100
1 country
1
Brief Summary
Transcranial Magnetic Stimulation is used to modulate the auditory neural pathways caused by hearing loss and leading to the phantom auditory perception of sound in the absence of an external or internal acoustic stimulus.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for not_applicable
Started Apr 2009
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
April 1, 2009
CompletedFirst Submitted
Initial submission to the registry
April 6, 2009
CompletedFirst Posted
Study publicly available on registry
April 7, 2009
CompletedPrimary Completion
Last participant's last visit for primary outcome
August 1, 2010
CompletedStudy Completion
Last participant's last visit for all outcomes
August 1, 2010
CompletedNovember 15, 2010
November 1, 2010
1.3 years
April 6, 2009
November 12, 2010
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
tinnitus severity as measured by the Tinnitus Questionnaire of Goebel and Hiller
Baseline, Day 12
Study Arms (2)
1
EXPERIMENTALCombined frontal and temporal transcranial magnetic stimulation
2
EXPERIMENTALTemporal transcranial magnetic stimulation
Interventions
Experimental repetitive transcranial magnetic stimulation (Alpine Biomed Mag Pro Option): 2000 stimuli of 20Hz rTMS over the left DLPFC (110% motor threshold) followed by 2000 stimuli of 1 Hz rTMS over the left temporal cortex DLPFC (110% motor threshold)
Experimental repetitive transcranial magnetic stimulation (Alpine Biomed Mag Pro Option): 2000 stimuli of 1 Hz rTMS over the left temporal cortex DLPFC (110% motor threshold)
Eligibility Criteria
You may qualify if:
- Diagnosis of subjective chronic tinnitus
- Duration of tinnitus more than 3 months
You may not qualify if:
- Objective tinnitus
- Treatable cause of the tinnitus
- Involvement in other treatments for tinnitus at the same time
- Clinically relevant psychiatric comorbidity
- Clinically relevant unstable internal or neurological comorbidity
- History of or evidence of significant brain malformation or neoplasm, head injury
- Cerebral vascular events
- Neurodegenerative disorder affecting the brain or prior brain surgery;
- Metal objects in and around body that can not be removed
- Pregnancy
- Alcohol or drug abuse
- Prior treatment with TMS
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
University of Regensburg - Dept of Psychiatry
Regensburg, Bavaria, 93053, Germany
Related Links
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Berthold Langguth, MD
University of Regensburg-Dept of Psychiatry
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- SINGLE
- Who Masked
- PARTICIPANT
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
Study Record Dates
First Submitted
April 6, 2009
First Posted
April 7, 2009
Study Start
April 1, 2009
Primary Completion
August 1, 2010
Study Completion
August 1, 2010
Last Updated
November 15, 2010
Record last verified: 2010-11