NCT00876278

Brief Summary

Pilot study to evaluate usability of Mesotest II for assessment of night driving capacity of pseudo-phakic patients implanted with aspheric monofocal posterior chamber IOL \*AT.Smart 46LC. Target Criterion: Measurement of contrast sensitivity and sensitivity to light under mesopic conditions (Mesotest II, Oculus).

Trial Health

30
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Timeline
Completed

Started Jun 2009

Shorter than P25 for phase_4

Geographic Reach
1 country

1 active site

Status
withdrawn

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

April 3, 2009

Completed
3 days until next milestone

First Posted

Study publicly available on registry

April 6, 2009

Completed
2 months until next milestone

Study Start

First participant enrolled

June 1, 2009

Completed
4 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 1, 2009

Completed
4 months until next milestone

Study Completion

Last participant's last visit for all outcomes

February 1, 2010

Completed
Last Updated

November 28, 2013

Status Verified

November 1, 2013

Enrollment Period

4 months

First QC Date

April 3, 2009

Last Update Submit

November 27, 2013

Conditions

Keywords

CataractIntraocular Lens (IOL)Mesotest IIEvaluation of usability of Mesotest II for assessment of night driving capacity of pseudo-phakic patients

Outcome Measures

Primary Outcomes (1)

  • Measurement of contrast sensitivity and sensitivity to light under mesopic conditions (Mesotest II, Oculus).

    8 months

Study Arms (1)

*AT.Smart 46LC

OTHER

The \*AT.Smart 46LC is indicated for primary implantation for the visual correction of aphakia in persons in whom the cataractous lens has been removed by phacoemulsification extracapsular cataract extraction. The IOL is intended to be placed only in an intact capsular bag. When implanted, the \*AT.Smart 46LC replaces the natural lens of the eye and functions as a refracting medium in the correction of aphakia.

Device: *AT.Smart 46LC

Interventions

Primary implantation of \*AT.Smart 46 LC into the eye's capsular bag for the visual correction of aphakia in persons in whom the cataractous lens has been removed by phacoemulsification extracapsular cataract extraction. The IOL is intended to be placed only in an intact capsular bag. When implanted, the \*AT.Smart 46LC replaces the natural lens of the eye and functions as a refracting medium in the correction of aphakia.

*AT.Smart 46LC

Eligibility Criteria

Age50 Years - 75 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Healthy eyes with cataract
  • Patient age 50-75 years
  • Written Patient Informed Consent
  • Assured follow-up examination

You may not qualify if:

  • Any kind of macula degeneration and impairment of retina (clinical diagnosis)
  • Amblyopia
  • Intraoperative complications; damaged posterior bag; intraocular haemorrhage
  • Astigmatism \> 1.5 D (objective, preoperative)
  • Pregnancy or lactation period for female patients

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Klinikum Augsburg, Klinik für Augenheilkunde

Augsburg, 86156, Germany

Location

MeSH Terms

Conditions

Cataract

Condition Hierarchy (Ancestors)

Lens DiseasesEye Diseases

Study Officials

  • Arthur J. Mueller, MD

    Klinikum Augsburg, Klinik für Augenheilkunde

    PRINCIPAL INVESTIGATOR
0

Study Design

Study Type
interventional
Phase
phase 4
Allocation
NON RANDOMIZED
Masking
NONE
Intervention Model
SINGLE GROUP
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

April 3, 2009

First Posted

April 6, 2009

Study Start

June 1, 2009

Primary Completion

October 1, 2009

Study Completion

February 1, 2010

Last Updated

November 28, 2013

Record last verified: 2013-11

Locations