NCT00875290

Brief Summary

The purpose of this study is to see if the use of a real-time glucose sensor improves diabetes control in young children (less than 4 years old) with Type I diabetes when they are initiated on insulin pump therapy.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
40

participants targeted

Target at below P25 for phase_3

Timeline
Completed

Started Nov 2008

Longer than P75 for phase_3

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

November 1, 2008

Completed
5 months until next milestone

First Submitted

Initial submission to the registry

April 2, 2009

Completed
1 day until next milestone

First Posted

Study publicly available on registry

April 3, 2009

Completed
5.6 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 1, 2014

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

November 1, 2014

Completed
Last Updated

August 5, 2011

Status Verified

August 1, 2011

Enrollment Period

6 years

First QC Date

April 2, 2009

Last Update Submit

August 4, 2011

Conditions

Keywords

Diabetes Mellitus, Type IChildrenInsulin pump therapyContinuous glucose monitor

Outcome Measures

Primary Outcomes (1)

  • Reduce blood glucose variability among 0-3 year old children with type I diabetes.

    1 year

Secondary Outcomes (1)

  • Number of adverse events

    1 year

Study Arms (2)

Control

NO INTERVENTION

Observational arm

Real-time glucose sensor

EXPERIMENTAL

Subjects wear real-time glucose sensor

Device: Real-time glucose sensor

Interventions

Children assigned to this intervention will use a real-time sensor continuously

Also known as: Minimed Paradigm Real-time sensor
Real-time glucose sensor

Eligibility Criteria

Age3 Months - 3 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17)

You may qualify if:

  • Children less than 4 years of age with Type I diabetes for at least 3 months

You may not qualify if:

  • Children greater than 4 years of age
  • Monogenic diabetes

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Seattle Children's Hospital

Seattle, Washington, 98105, United States

RECRUITING

MeSH Terms

Conditions

Diabetes Mellitus, Type 1

Condition Hierarchy (Ancestors)

Diabetes MellitusGlucose Metabolism DisordersMetabolic DiseasesNutritional and Metabolic DiseasesEndocrine System DiseasesAutoimmune DiseasesImmune System Diseases

Study Officials

  • Patricia Fechner, MD

    Seattle Children's Hospital

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Study Design

Study Type
interventional
Phase
phase 3
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER

Study Record Dates

First Submitted

April 2, 2009

First Posted

April 3, 2009

Study Start

November 1, 2008

Primary Completion

November 1, 2014

Study Completion

November 1, 2014

Last Updated

August 5, 2011

Record last verified: 2011-08

Locations