Study Investigating Tooth Movements With Conventional and Computer-Aided Design/Computer-Aided Manufacturing (CAD/CAM) Supported Fixed Appliances

NCT00871091 | Unknown

• 1 other identifier: JO 207/4-1-4
• Study Type: interventional
• Target: 32
• Locations: 1 country
• Sites: 1

Brief Summary

In orthodontics, conventional fixed appliances, usually consisting of prefabricated components, require step-by-step adjustment in order to move teeth in the planned direction. May treatment be improved with customized archwires? Study hypotheses:

• By using CAD/CAM in planning and fabrication of customized archwires, unnecessary tooth movements can be avoided and teeth can be moved on their direct path to the intended position.
• The application of CAD/CAM improves reproducibility, efficiency, and quality of orthodontic treatment.

Conditions

Tooth Movement; Orthodontics

Keywords

CAD/CAM; orthodontics; fixed appliance; tooth movement

Outcome Measures

Primary Outcomes (1)

• Sum of differences between resulted and shortest path of tooth movements in each patient

  measurements every 14 days until end of treatment

Secondary Outcomes (1)

• Difference between resulted and shortest path of movements for each tooth

  measurements every 14 days until end of treatment

Study Arms (3)

1

EXPERIMENTAL

CAD/CAM group, customized archwires

Procedure: orthodontic treatment with customized archwires

2

ACTIVE COMPARATOR

prefabricated archwires (superelastic)

Procedure: orthodontic treatment with prefabricated archwires

3

ACTIVE COMPARATOR

prefabricated archwires with manual adjustments

Procedure: orthodontic tx w/ conventional archwires+manual adjustments

Interventions

orthodontic treatment with customized archwires PROCEDURE

customized arch wires depending on the amount of needed tooth movement

Also known as: SureSmile, CAD/CAM

1

orthodontic treatment with prefabricated archwires PROCEDURE

prefabricated archwires depending of the needed movement of the teeth

Also known as: archwires, prefabricated, conventional orthodontic treatment

2

orthodontic tx w/ conventional archwires+manual adjustments PROCEDURE

conventional archwires modified by manual adjustment, depending of needed correction

Also known as: manual adjustment, conventionel archwires

3

Eligibility Criteria

• Age: 18 Years - 35 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• treatment of front teeth with fixed orthodontic appliances is indicated
• complete secondary dentition
• age: 18-35
• in healthy general condition
• patient is informed about study and agrees to participate

You may not qualify if:

• treatment of premolars and molars is necessary
• syndromes affecting bones and teeth
• cleft lip and palate
• inflammation or reduction (more than 50%) of periodontium
• intake of drugs affecting tooth movement and bone formation
• disturbance of bone formation
• disturbance of thyroidal function
• pregnancy
• participation in additional study affecting oral hygiene
• former therapy with ionized radiation or cytostatic drugs
• caries (active phase)
• alcohol dependency

Sponsors & Collaborators

• Charite University, Berlin, Germany: lead
• German Research Foundation: collaborator

Study Sites (1)

Department of Orthodontics, Dentofacial Orthopedics and Pedodontics, Charité - Universitätsmedizin Berlin

Berlin, 14197, Germany

Location

MeSH Terms

Interventions

Orthodontics

Intervention Hierarchy (Ancestors)

Dentistry

Study Officials

• Paul-Georg Jost-Brinkmann, Prof

  Charite - Universitätsmedizin

  STUDY CHAIR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER

Study Record Dates

• First Submitted: March 27, 2009
• First Posted: March 30, 2009
• Study Start: January 1, 2007
• Primary Completion: May 1, 2009
• Study Completion: June 1, 2009
• Last Updated: March 30, 2009

Record last verified: 2009-03

Locations

DE (1)