Case Volume and Adenoma Rate During Screening Colonoscopy

NCT00860665 | Completed

• 1 other identifier: BECOP-3
• Study Type: observational
• Target: 12,134
• Locations: 1 country
• Sites: 1

Brief Summary

Screening colonoscopy has been established as the most effective means of colorectal cancer prevention. This is based on the fact that colonoscopy detects and removes colonic polyps (adenomas) which are known to progress to cancer if left untreated. The present study examines the question whether case volume (i.e., the number of colonoscopies performed per year) correlates with colonoscopy quality, i.e., adenoma detection rate.

Conditions

Colorectal Cancer

Keywords

colorectal cancer; prevention; colonoscopy; screening; quality assessment; colorectal cancer prevention

Outcome Measures

Primary Outcomes (1)

• Correlation of adenoma detection rate with case volume of endoscopists

  18 months

Secondary Outcomes (1)

• Patient acceptance in relation to procedural factors (e.g. sedation)

  18 months

Study Arms (1)

1

Observational study on consecutive persons over the age of 55 years presenting for screening colonoscopy

Eligibility Criteria

• Age: 55 Years - 85 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

In Germany screening colonoscopy is reimbursed over the age of 55 years. All persons willing to undergo screening colonsocopy without contraindications are asked for consent to be included

You may qualify if:

• all persons willing and able to undergo screening colonoscopy over the age of 55 years

You may not qualify if:

• any condition not compatible with the definition of screening colonoscopy

Sponsors & Collaborators

• Charite University, Berlin, Germany: lead
• Interest group of Berlin private practice gastroenterologists: collaborator

Study Sites (1)

Charité Medical University Berlin Campus Virchow

Berlin, State of Berlin, 13353, Germany

Location

Related Publications (3)

• Adler A, Lieberman D, Aminalai A, Aschenbeck J, Drossel R, Mayr M, Mross M, Scheel M, Schroder A, Keining C, Stange G, Wiedenmann B, Gauger U, Altenhofen L, Rosch T. Data quality of the German screening colonoscopy registry. Endoscopy. 2013 Oct;45(10):813-8. doi: 10.1055/s-0033-1344583. Epub 2013 Sep 9.

  PMID: 24019130 DERIVED

• Adler A, Wegscheider K, Lieberman D, Aminalai A, Aschenbeck J, Drossel R, Mayr M, Mross M, Scheel M, Schroder A, Gerber K, Stange G, Roll S, Gauger U, Wiedenmann B, Altenhofen L, Rosch T. Factors determining the quality of screening colonoscopy: a prospective study on adenoma detection rates, from 12,134 examinations (Berlin colonoscopy project 3, BECOP-3). Gut. 2013 Feb;62(2):236-41. doi: 10.1136/gutjnl-2011-300167. Epub 2012 Mar 22.

  PMID: 22442161 DERIVED

• Adler A, Aminalai A, Aschenbeck J, Drossel R, Mayr M, Scheel M, Schroder A, Yenerim T, Wiedenmann B, Gauger U, Roll S, Rosch T. Latest generation, wide-angle, high-definition colonoscopes increase adenoma detection rate. Clin Gastroenterol Hepatol. 2012 Feb;10(2):155-9. doi: 10.1016/j.cgh.2011.10.026. Epub 2011 Nov 2.

  PMID: 22056301 DERIVED

MeSH Terms

Conditions

Colorectal Neoplasms

Condition Hierarchy (Ancestors)

Intestinal Neoplasms; Gastrointestinal Neoplasms; Digestive System Neoplasms; Neoplasms by Site; Neoplasms; Digestive System Diseases; Gastrointestinal Diseases; Colonic Diseases; Intestinal Diseases; Rectal Diseases

Study Officials

• Thomas Rösch, MD

  Department of Interdisciplinary Endoscopy, Hamburg University Eppendorf, Germany

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER

Study Record Dates

• First Submitted: March 11, 2009
• First Posted: March 12, 2009
• Study Start: October 1, 2006
• Primary Completion: March 1, 2008
• Study Completion: March 1, 2009
• Last Updated: March 12, 2009

Record last verified: 2009-03

Locations

DE (1)