NCT00858286

Brief Summary

The purpose with this study is to describe in detail the control or lack of control of asthma, based on two different dosing strategies, regular treatment with SERETIDE in a stable dosing with short acting beta-2 agonists as needed, or maintenance treatment with SYMBICORT and using the same inhaler with SYMBICORT as needed.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
56

participants targeted

Target at P25-P50 for phase_4 asthma

Timeline
Completed

Started Feb 2009

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 1, 2009

Completed
18 days until next milestone

First Submitted

Initial submission to the registry

February 19, 2009

Completed
18 days until next milestone

First Posted

Study publicly available on registry

March 9, 2009

Completed
1.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 1, 2010

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

April 1, 2010

Completed
Last Updated

August 13, 2014

Status Verified

August 1, 2014

Enrollment Period

1.2 years

First QC Date

February 19, 2009

Last Update Submit

August 11, 2014

Conditions

Outcome Measures

Primary Outcomes (1)

  • asthma control based on GINA guidelines from 2007.

    3 months

Secondary Outcomes (1)

  • Quality of Life, Health economics and exacerbations

    3 months

Study Arms (2)

Stable dosing with SERETIDE, short acting B-2agonist as needed

EXPERIMENTAL

Regular treatment with SERETIDE in a stable dosing with short acting beta-2 agonists as needed

Other: Spirometry, PEF measurements and diary cards to evaluate control of Asthma

Maintenance treatment with SYMBICORT and SYMBICORT as needed

EXPERIMENTAL

Maintenance treatment with SYMBICORT and using the same inhaler with SYMBICORT as needed

Other: Spirometry, PEF measurements and diary cards to evaluate control of Asthma

Interventions

No intervention is made with the existing therapy, but patient will perform spirometry and PEF evaluations together with a registration of control of asthma in diary cards and health economic parameters in questionnaires

Maintenance treatment with SYMBICORT and SYMBICORT as neededStable dosing with SERETIDE, short acting B-2agonist as needed

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • written informed consent
  • years or above
  • able to fill in questionnaires and perform PEF measurements
  • asthma diagnosis and prescribed SERETIDE or SYMBICORT, either regular treatment using SERETIDE in a stable dosing and short acting B2 agonists as needed, or maintenance treatment with SYMBICORT but also using same inhaler SYMBICORT as needed

You may not qualify if:

  • no other lung disease
  • neurological disease with psychological handicap
  • cerebro-vascular disease with handicap
  • un-stable cancer
  • known or planned pregnancy during the time of the study
  • subjects who have serious uncontrolled disease

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

GSK Investigational Site

Stockholm, SE-171 77, Sweden

Location

MeSH Terms

Conditions

Asthma

Condition Hierarchy (Ancestors)

Bronchial DiseasesRespiratory Tract DiseasesLung Diseases, ObstructiveLung DiseasesRespiratory HypersensitivityHypersensitivity, ImmediateHypersensitivityImmune System Diseases

Study Officials

  • GSK Clinical Trials

    GlaxoSmithKline

    STUDY DIRECTOR

Study Design

Study Type
interventional
Phase
phase 4
Allocation
NON RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

February 19, 2009

First Posted

March 9, 2009

Study Start

February 1, 2009

Primary Completion

April 1, 2010

Study Completion

April 1, 2010

Last Updated

August 13, 2014

Record last verified: 2014-08

Locations