Microarray Analysis of Sinus Samples From Patients With and Without Chronic Rhinosinusitis.

NCT00847041 | Completed

• 1 other identifier: A109753
• Study Type: observational
• Target: N/A
• Locations: 0 countries
• Sites: N/A

Brief Summary

The purpose of this study is to compare the bacteria, fungi, and viruses that are present in the sinuses of patients with chronic rhinosinusitis to patients without sinus disease using a new technology, called a microarray, that will allow more accurate identification of microorganisms than current laboratory methods.

Conditions

Chronic Rhinosinusitis

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Twenty total patients are being recruited: ten adult patients who meet the clinical criteria for chronic rhinosinusitis requiring surgical therapy and ten adult patients undergoing either orbital decompression for Graves' orbitopathy or maxillomandibular advancement for obstructive sleep apnea, with no history of sinus disease.

You may qualify if:

• Age 18 years or older
• History of chronic rhinosinusitis (CRS)
• Impaired CRS-specific quality of life
• Evidence of sinus disease on a CT scan

You may not qualify if:

• Control patients with any evidence of CRS by history, survey, or imaging criteria

Sponsors & Collaborators

• University of California, San Francisco: lead

Study Design

• Study Type: observational
• Sponsor Type: OTHER

Study Record Dates

• First Submitted: February 18, 2009
• First Posted: February 19, 2009
• Last Updated: February 19, 2009

Record last verified: 2009-02