NCT00845208

Brief Summary

Relapse is the most serious problem in alcoholism treatment. The overall aim of the present study was to determine if a treatment directed at changing the patient's social network, from one that reinforces drinking behavior to one that reinforces sobriety, can create the conditions necessary for long-term treatment success. In addition, we intended to determine if explicit reinforcement for this change of social network (Contingency Management or ContM) would be more effective than the same network support intervention without contingent reinforcement for change.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
210

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Mar 2002

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

March 1, 2002

Completed
5.6 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 1, 2007

Completed
4 months until next milestone

Study Completion

Last participant's last visit for all outcomes

February 1, 2008

Completed
1 year until next milestone

First Submitted

Initial submission to the registry

February 17, 2009

Completed
1 day until next milestone

First Posted

Study publicly available on registry

February 18, 2009

Completed
Last Updated

May 9, 2023

Status Verified

May 1, 2023

Enrollment Period

5.6 years

First QC Date

February 17, 2009

Last Update Submit

May 8, 2023

Conditions

Alcohol Dependence

Keywords

Network SupportAAContingency Management

Outcome Measures

Primary Outcomes (1)

  • Proportion Days Abstinent

    Every 3 months out to 2 years

Secondary Outcomes (1)

  • Network Support for Abstinence

    every 6 months out to 2 years

Study Arms (3)

Case Management

ACTIVE COMPARATOR
Behavioral: Network Support

Network Support

EXPERIMENTAL

12 Weekly sessions intended to help patients change their social networks to be more supportive of abstinence

Behavioral: Network Support

Network Support + Contingency Mgmnt

EXPERIMENTAL

12 weekly sessions intended to help patients change their social networks to be more supportive of abstinence. Contingency management component added to reinforce efforts to make network changes.

Behavioral: Network Support

Interventions

Network SupportBEHAVIORAL

12 Weekly sessions intended to help patients change their social networks to be more supportive of abstinence

Case ManagementNetwork SupportNetwork Support + Contingency Mgmnt

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • meet DSM-IV criteria for Alcohol Dependence
  • at least 18 years old
  • Willing to accept random assignment to treatment conditions

You may not qualify if:

  • acute medical or psychiatric problems that require inpatient treatment
  • reading ability below the fifth grade level
  • lack of reliable transportation to the treatment site
  • excessive commuting distance to site
  • current dependence on drugs (except marijuana)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Connecticut health Center

Farmington, Connecticut, 06030, United States

Location

Related Publications (3)

  • Litt MD, Kadden RM, Kabela-Cormier E, Petry N. Changing network support for drinking: initial findings from the network support project. J Consult Clin Psychol. 2007 Aug;75(4):542-55. doi: 10.1037/0022-006X.75.4.542.

    PMID: 17663609RESULT

  • Litt MD, Kadden RM, Kabela-Cormier E, Petry NM. Changing network support for drinking: network support project 2-year follow-up. J Consult Clin Psychol. 2009 Apr;77(2):229-42. doi: 10.1037/a0015252.

    PMID: 19309183RESULT

  • Litt MD, Kadden RM, Tennen H. Treatment response and non-response in CBT and Network Support for alcohol disorders: targeted mechanisms and common factors. Addiction. 2018 Aug;113(8):1407-1417. doi: 10.1111/add.14224. Epub 2018 Apr 20.

    PMID: 29575339DERIVED

MeSH Terms

Conditions

Alcoholism

Interventions

Support Vector Machine

Condition Hierarchy (Ancestors)

Alcohol-Related DisordersSubstance-Related DisordersChemically-Induced DisordersMental Disorders

Intervention Hierarchy (Ancestors)

Supervised Machine LearningMachine LearningArtificial IntelligenceAlgorithmsMathematical ConceptsClassification Algorithms

Study Officials

  • Mark D Litt, PhD

    UConn Health

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor

Study Record Dates

First Submitted

February 17, 2009

First Posted

February 18, 2009

Study Start

March 1, 2002

Primary Completion

October 1, 2007

Study Completion

February 1, 2008

Last Updated

May 9, 2023

Record last verified: 2023-05

Locations

US(1)