NCT00839735

Brief Summary

The study focuses on trefoil family factor (TFF) peptides in sputum in lung diseases. The investigators hypothesize that TFF peptides are upregulated in lung diseases characterized by mucus hypersecretion.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
60

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started Feb 2009

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 1, 2009

Completed
5 days until next milestone

First Submitted

Initial submission to the registry

February 6, 2009

Completed
3 days until next milestone

First Posted

Study publicly available on registry

February 9, 2009

Completed
1.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 1, 2010

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

May 1, 2010

Completed
Last Updated

February 17, 2021

Status Verified

February 1, 2021

Enrollment Period

1.2 years

First QC Date

February 6, 2009

Last Update Submit

February 14, 2021

Conditions

Chronic Obstructive Pulmonary DiseaseAsthma

Keywords

COPD

Outcome Measures

Primary Outcomes (1)

  • TFF in sputum

    Monthly

Study Arms (3)

COPD

Chronic obstructive pulmonary disease

Asthma

Healthy controls

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

Subjects with chronic obstruction pulmonary disease (COPD) Subjects with asthma Healthy volunteers

You may qualify if:

  • Age 18 years or older
  • Informed consent

You may not qualify if:

  • Upper and lower airway infection 2 weeks prior to visit 1

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Respiratory and Allergy Research Unit, Department of Respiratory Medicine L, Bispebjerg Hospital

Copenhagen, 2400, Denmark

Location

MeSH Terms

Conditions

Pulmonary Disease, Chronic ObstructiveAsthma

Condition Hierarchy (Ancestors)

Lung Diseases, ObstructiveLung DiseasesRespiratory Tract DiseasesChronic DiseaseDisease AttributesPathologic ProcessesPathological Conditions, Signs and SymptomsBronchial DiseasesRespiratory HypersensitivityHypersensitivity, ImmediateHypersensitivityImmune System Diseases

Study Officials

  • Thomas K Lund, MD PhD

    Respiratory and Allergy Research Unit

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
MD

Study Record Dates

First Submitted

February 6, 2009

First Posted

February 9, 2009

Study Start

February 1, 2009

Primary Completion

May 1, 2010

Study Completion

May 1, 2010

Last Updated

February 17, 2021

Record last verified: 2021-02

Locations

DK(1)