Evaluation of Apathy Using Attentional Reaction Test in Neurodegenerative Diseases
1 other identifier
interventional
70
1 country
1
Brief Summary
Apathy, defined as a lack of motivation in behaviour, cognition and affect, is common in neurodegenerative diseases. Specific scales are available for the evaluation of apathy but it lacks objective evaluation methods. The aim of this study is to evaluate the changes in reaction time task according to the presence or absence of reward stimulation and to assess the relation between these performances and apathy scales.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for not_applicable alzheimer-disease
Started Feb 2009
Typical duration for not_applicable alzheimer-disease
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
January 28, 2009
CompletedStudy Start
First participant enrolled
February 1, 2009
CompletedFirst Posted
Study publicly available on registry
February 2, 2009
CompletedPrimary Completion
Last participant's last visit for primary outcome
October 1, 2011
CompletedStudy Completion
Last participant's last visit for all outcomes
October 1, 2011
CompletedDecember 9, 2011
December 1, 2011
2.7 years
January 28, 2009
December 8, 2011
Conditions
Outcome Measures
Primary Outcomes (1)
Reaction times (ms), using a computerized test
one time point, at day 0 (day of inclusion) during the computerized test
Secondary Outcomes (1)
Apathy severity, using a specific apathy scale (Apathy Inventory)
one time point, at day 0 (day of inclusion), during the visit
Study Arms (1)
1
EXPERIMENTALUsing a computerized test, each patient is asked to press a button (mouse of the computer) each time the screen of the computer becomes completely white.
Interventions
Using a computerized test, each patient is asked to press a button (mouse of the computer) each time the screen of the computer becomes completely white.
Eligibility Criteria
You may qualify if:
- Elderly patients with diagnosis of Alzheimer's Disease according to DSM-IV criteria
- MMSE \>20
You may not qualify if:
- None
- Motor or psychiatric disorders
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
CM2R, Nice University Hospital
Nice, 06000, France
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Masking
- NONE
- Purpose
- DIAGNOSTIC
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
January 28, 2009
First Posted
February 2, 2009
Study Start
February 1, 2009
Primary Completion
October 1, 2011
Study Completion
October 1, 2011
Last Updated
December 9, 2011
Record last verified: 2011-12