Urobilinogen, Maternal Weight Loss and Impending Parturition at Term

NCT00826605 | Completed DMC

• 1 other identifier: 200802
• Study Type: observational
• Target: 200
• Locations: 1 country
• Sites: 2

Brief Summary

The purpose of this study, then, is to search existing clinic and hospital records for answers to the following two questions: (1) Do pregnant women who are at least 37 weeks gestation and who have an increase in urubilinogen on urine dipstick at a prenatal appointment have a statistically significant shorter average time before going into active labor than their negative counterparts? (2) Do pregnant women who are at least 37 weeks gestation and who show a modest weight loss between two prenatal appointments have a statistically significant shorter average time before going into active labor than their counterparts who did not lose weight?

Conditions

Increase in Urobilinogen in Urine Prior to Delivery; Weight Loss After 37 Weeks Gestation Prior to Delivery

Keywords

Weight loss, urobilinogen

Outcome Measures

Primary Outcomes (1)

• Increase in urobilinogen on routine urine dipstick at prenatal appointment, term pregnancy

  none--chart review

Secondary Outcomes (1)

• Maternal weight loss at term before giving birth

  none--chart review

Study Arms (2)

Urobilinogen increase

Increase in urobilinogen increase on routine dipstick test at prenatal appointment after 37 weeks gestation

Weight Loss at Term

Weight loss since previous prenatal appointment after 37 weeks gestation

Eligibility Criteria

• Age: 18 Years - 34 Years
• Sex: female
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)
• Sampling Method: Probability Sample

Study Population

Population is mothers between the ages of 18 and 34 years of age with a single intrauterine pregnancy between 37 weeks and 41 weeks gestational age. (Both very young mothers and women 35 and older have increased risk of premature delivery.) The patients will have an admission diagnosis of either active labor or spontaneous rupture of membranes. Active labor is defined as uterine contractions resulting in changes either in the cervical dilatation, the effacement of the cervix and/or descent of the fetal head in the pelvis.

Sponsors & Collaborators

• Oklahoma State University Center for Health Sciences: lead

Study Sites (2)

OSU Houston Center OB/Gyn Clinic

Tulsa, Oklahoma, 74127, United States

Location

OSU Medical Center

Tulsa, Oklahoma, 74127, United States

Location

MeSH Terms

Conditions

Weight Loss

Condition Hierarchy (Ancestors)

Body Weight Changes; Body Weight; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Officials

• Elizabeth Harris, DO

  OSU Center for Health Sciences

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER

Study Record Dates

• First Submitted: January 20, 2009
• First Posted: January 22, 2009
• Study Start: January 1, 2009
• Primary Completion: July 1, 2009
• Study Completion: October 1, 2009
• Last Updated: January 28, 2010

Record last verified: 2010-01

Locations

US (2)