NCT00824629

Brief Summary

The purpose of this study is to evaluate two types of embryo transfer procedure. The investigators will compare direct embryo transfer against afterloading embryo transfer.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
400

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Oct 2008

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 1, 2008

Completed
4 months until next milestone

First Submitted

Initial submission to the registry

January 16, 2009

Completed
3 days until next milestone

First Posted

Study publicly available on registry

January 19, 2009

Completed
1.6 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 1, 2010

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

September 1, 2010

Completed
Last Updated

October 26, 2010

Status Verified

August 1, 2009

Enrollment Period

1.9 years

First QC Date

January 16, 2009

Last Update Submit

October 25, 2010

Conditions

Infertility

Keywords

Embryo transferIVFUltrasound embryo transfer

Outcome Measures

Primary Outcomes (1)

  • Clinical pregnancy

    8 weeks after embryo transfer

Secondary Outcomes (2)

  • Difficulty of embryo transfer

    During embryo transfer procedure

  • Duration of embryo transfer

    During embryo transfer procedure

Study Arms (2)

1

EXPERIMENTAL

Afterloading embryo transfer procedure

Procedure: Afterloading embryo transfer procedure

2

ACTIVE COMPARATOR

Direct embryo transfer procedure

Procedure: Direct embryo transfer procedure

Interventions

Afterloading embryo transfer procedurePROCEDURE

Afterloading embryo transfer procedure

1
Direct embryo transfer procedurePROCEDURE

Direct embryo transfer procedure

2

Eligibility Criteria

Age18 Years - 42 Years
Sexfemale
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • Patients in IVF/CICSI program
  • Transfer day:2 or 3 after ovum pick-up

You may not qualify if:

  • None

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Departamento de Obstetricia Ginecologia y Reproducción. Institut Universitari Dexeus

Barcelona, Barcelona, 08037, Spain

Location

Related Publications (6)

  • Coroleu B, Carreras O, Veiga A, Martell A, Martinez F, Belil I, Hereter L, Barri PN. Embryo transfer under ultrasound guidance improves pregnancy rates after in-vitro fertilization. Hum Reprod. 2000 Mar;15(3):616-20. doi: 10.1093/humrep/15.3.616.

    PMID: 10686207BACKGROUND

  • Coroleu B, Barri PN, Carreras O, Martinez F, Parriego M, Hereter L, Parera N, Veiga A, Balasch J. The influence of the depth of embryo replacement into the uterine cavity on implantation rates after IVF: a controlled, ultrasound-guided study. Hum Reprod. 2002 Feb;17(2):341-6. doi: 10.1093/humrep/17.2.341.

    PMID: 11821275BACKGROUND

  • Coroleu B, Barri PN, Carreras O, Martinez F, Veiga A, Balasch J. The usefulness of ultrasound guidance in frozen-thawed embryo transfer: a prospective randomized clinical trial. Hum Reprod. 2002 Nov;17(11):2885-90. doi: 10.1093/humrep/17.11.2885.

    PMID: 12407044BACKGROUND

  • Coroleu B, Barri PN, Carreras O, Belil I, Buxaderas R, Veiga A, Balasch J. Effect of using an echogenic catheter for ultrasound-guided embryo transfer in an IVF programme: a prospective, randomized, controlled study. Hum Reprod. 2006 Jul;21(7):1809-15. doi: 10.1093/humrep/del045. Epub 2006 Mar 23.

    PMID: 16556674BACKGROUND

  • Matorras R, Mendoza R, Exposito A, Rodriguez-Escudero FJ. Influence of the time interval between embryo catheter loading and discharging on the success of IVF. Hum Reprod. 2004 Sep;19(9):2027-30. doi: 10.1093/humrep/deh366. Epub 2004 Jun 10.

    PMID: 15192071BACKGROUND

  • Neithardt AB, Segars JH, Hennessy S, James AN, McKeeby JL. Embryo afterloading: a refinement in embryo transfer technique that may increase clinical pregnancy. Fertil Steril. 2005 Mar;83(3):710-4. doi: 10.1016/j.fertnstert.2004.08.022.

    PMID: 15749502BACKGROUND

Related Links

MeSH Terms

Conditions

Infertility

Condition Hierarchy (Ancestors)

Genital DiseasesUrogenital Diseases

Study Officials

  • Buenaventura Coroleu, PhD., MD.

    Departamento de Obstetricia, Ginecologia y Reproduccion , Institut Universitari Dexeus

    STUDY DIRECTOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, INVESTIGATOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER

Study Record Dates

First Submitted

January 16, 2009

First Posted

January 19, 2009

Study Start

October 1, 2008

Primary Completion

September 1, 2010

Study Completion

September 1, 2010

Last Updated

October 26, 2010

Record last verified: 2009-08

Locations

ES(1)