NCT00820937

Brief Summary

The aim of this study is to improve the diagnostic of Lewy body dementia by combining the scintigraphy (SPECT) usig a spécific transporter and magnetic resonance imaging (MRI).

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
20

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Mar 2006

Typical duration for not_applicable

Geographic Reach
1 country

3 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

March 1, 2006

Completed
2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 1, 2008

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

March 1, 2008

Completed
10 months until next milestone

First Submitted

Initial submission to the registry

December 27, 2008

Completed
16 days until next milestone

First Posted

Study publicly available on registry

January 12, 2009

Completed
Last Updated

July 30, 2025

Status Verified

August 1, 2009

Enrollment Period

2 years

First QC Date

December 27, 2008

Last Update Submit

July 28, 2025

Conditions

Lewy Body Dementia

Outcome Measures

Primary Outcomes (1)

  • SPECT and MRI differential imaging

    Visit 1

Secondary Outcomes (1)

  • Neuropsychological analysis

    Visit 1

Interventions

Single photon emission computed tomography and Magnetic Resonance ImagingPROCEDURE

Eligibility Criteria

Age65 Years - 90 Years
Sexall
Healthy VolunteersNo
Age GroupsOlder Adult (65+)

You may qualify if:

  • Patients with alzheimer disease following NINCDS-ADRDA scale or Lewy body dementia following Mc Keith scale.
  • Aged between 65 et 90 years
  • Patients with visual hallucination
  • Patients with helping people
  • Patients with MMSE (Mini Mental State Examination) equal or more than 18.
  • Signed consent

You may not qualify if:

  • Hospitalized patients without their consent
  • Patients who have not passed the neuropsychological tests
  • Patients with a MMSE less than 18
  • Patients without helping
  • Patients with no visual hallucinations
  • Patients with severe somatic pathology.
  • Pregnancy
  • Allergy to iodine

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (3)

Département de Gérontologie - Chu Limoges

Limoges, 87000, France

Location

Pôle de psychiatrie du sujet âgé - CH Esquirol

Limoges, 87000, France

Location

Service de Neurologie - CHU de Limoges

Limoges, 87000, France

Location

Related Publications (1)

  • Comparison of DAT-scan evaluation for the aetiological diagnosis of hallucinations in the elderly P. Thomas a,∗,d, A. Prado-Jeana,b, J.-P. Clément a,d, P. Couratier a,b, J. Monteil c NPG Neurologie - Psychiatrie - Gériatrie Volume 13, Issue 75, June 2013, Pages 145-151

    RESULT

MeSH Terms

Conditions

Lewy Body Disease

Interventions

Magnetic Resonance Spectroscopy

Condition Hierarchy (Ancestors)

Parkinsonian DisordersBasal Ganglia DiseasesBrain DiseasesCentral Nervous System DiseasesNervous System DiseasesDementiaMovement DisordersSynucleinopathiesNeurodegenerative DiseasesNeurocognitive DisordersMental Disorders

Intervention Hierarchy (Ancestors)

Spectrum AnalysisChemistry Techniques, AnalyticalInvestigative Techniques

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Purpose
DIAGNOSTIC
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER

Study Record Dates

First Submitted

December 27, 2008

First Posted

January 12, 2009

Study Start

March 1, 2006

Primary Completion

March 1, 2008

Study Completion

March 1, 2008

Last Updated

July 30, 2025

Record last verified: 2009-08

Locations

FR(3)