NCT00819481

Brief Summary

The purpose of this study is to evaluate the use and efficacy of the 3DKnee™ System for total knee replacement surgery.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
229

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Feb 2009

Longer than P75 for all trials

Geographic Reach
1 country

8 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

January 8, 2009

Completed
1 day until next milestone

First Posted

Study publicly available on registry

January 9, 2009

Completed
23 days until next milestone

Study Start

First participant enrolled

February 1, 2009

Completed
4.9 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 1, 2014

Completed
4.8 years until next milestone

Study Completion

Last participant's last visit for all outcomes

October 1, 2018

Completed
Last Updated

March 16, 2021

Status Verified

February 1, 2017

Enrollment Period

4.9 years

First QC Date

January 8, 2009

Last Update Submit

March 15, 2021

Conditions

Keywords

Total knee replacement

Outcome Measures

Primary Outcomes (1)

  • efficacy of total knee system

    2 year

Secondary Outcomes (5)

  • change in Knee Society Score

    5 year

  • change in pain from pre-op to post-op

    5 year

  • patient satisfaction

    5 year

  • change in WOMAC Osteoarthritis Index from pre-surgery

    5 year

  • change in Oxford Knee Score from pre-surgery

    5 year

Study Arms (1)

3DKnee

Post Market Study

Device: 3DKnee™ System

Interventions

Total knee replacement joint for subjects with knee osteoarthritis and willing to participate in the study.

3DKnee

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Patients who are over 18 years of age and are candidates for a primary total knee replacement.

You may qualify if:

  • This must be a primary knee replacement on this knee.
  • Patient is over 18 years of age or older
  • Have knee joint disease related to one or more of the following
  • degenerative joint disease, including osteoarthritis or traumatic arthritis
  • Avascular necrosis of the femoral condyles
  • Post-traumatic loss of joint configuration, particularly when there is patellofemoral erosion, dysfunction or prior patellectomy
  • Moderate valgus, varus, or flexion deformities
  • Rheumatoid arthritis
  • Patient is likely to be available for evaluation for the duration of the study
  • Able and willing to sign the informed consent and follow study procedures
  • Patient is not pregnant

You may not qualify if:

  • Is younger than 18 years of age
  • If there has been a total knee replacement on this knee in the past (no revisions allowed in study)
  • Infection, or history of infection, acute or chronic, local or systemic
  • Alcoholism or other addictions
  • Muscular, neurological or vascular deficiencies which compromise the affected extremity
  • Obesity
  • Insufficient bone quality
  • Loss of ligamentous structures
  • High levels of physical activity
  • Materials sensitivity
  • Prisoner
  • Mental conditions that may interfere with the patient's ability to give an informed consent or willingness to fulfill the study requirements
  • Patient is pregnant

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (8)

Longo Orthopedics

Scottsdale, Arizona, 85251, United States

Location

Center for Excellence

Fresno, California, 93710, United States

Location

OrthoMaryland

Baltimore, Maryland, 21209, United States

Location

Metro Orthopedics and Sports Therapy

Silver Spring, Maryland, 20910, United States

Location

Leslie Orthopedics and Sports Medicine

Camdenton, Missouri, 65020, United States

Location

St. Peter's Bone & Joint Surgery

City of Saint Peters, Missouri, 63376, United States

Location

Texas Center for Joint Replacement

Plano, Texas, 75093, United States

Location

Rimrock Orthopedics

St. George, Utah, 84790, United States

Location

Related Links

MeSH Terms

Conditions

Joint DiseasesOsteoarthritisArthritis, Rheumatoid

Condition Hierarchy (Ancestors)

Musculoskeletal DiseasesArthritisRheumatic DiseasesConnective Tissue DiseasesSkin and Connective Tissue DiseasesAutoimmune DiseasesImmune System Diseases

Study Officials

  • John W. McAllister, M.D.

    St. Peter's Bone and Joint Surgery

    PRINCIPAL INVESTIGATOR
  • Barry J Waldman, M.D.

    OrthoMaryland

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

January 8, 2009

First Posted

January 9, 2009

Study Start

February 1, 2009

Primary Completion

January 1, 2014

Study Completion

October 1, 2018

Last Updated

March 16, 2021

Record last verified: 2017-02

Locations