NCT00817297

Brief Summary

The purpose of this study is to compare a new noninvasive ventilator to existing ventilators already used for patient care.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
16

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Jan 2009

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

January 3, 2009

Completed
3 days until next milestone

First Posted

Study publicly available on registry

January 6, 2009

Completed
11 days until next milestone

Study Start

First participant enrolled

January 17, 2009

Completed
2 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 3, 2009

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

April 7, 2009

Completed
Last Updated

November 17, 2017

Status Verified

April 1, 2017

Enrollment Period

2 months

First QC Date

January 3, 2009

Last Update Submit

November 13, 2017

Conditions

Keywords

noninvasive ventilation

Outcome Measures

Primary Outcomes (1)

  • Breathing comfort

    0, 15, and 30 minutes

Secondary Outcomes (1)

  • Physiological variables

    0, 15, and 30 minutes

Study Arms (2)

V60 Mask, Then Conventional Mask

OTHER

Experimental V60 Mask Ventilator for treating adult patients with COPD, then Comparator Conventional Mask Ventilator for treating adult patients with COPD

Device: noninvasive ventilator

Conventional Mask, Then V60 Mask

OTHER

Comparator Conventional Mask noninvasive Ventilator for treating adult patients with COPD, then Experimental V60 Mask noninvasive Ventilator for treating adult patients with COPD.

Device: noninvasive ventilator

Interventions

Experimental V60 Mask noninvasive Ventilator for treating patients with COPD, then Comparator Conventional Mask noninvasive Ventilator for treating patients with COPD in crossover study design

Conventional Mask, Then V60 MaskV60 Mask, Then Conventional Mask

Eligibility Criteria

Age18 Years - 85 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Age \> 18 years and \< 85 years
  • Weight \> 20 kg (44 lbs)
  • Respiratory failure or respiratory insufficiency
  • Ability to cooperate with the investigators

You may not qualify if:

  • An endotracheal tube or tracheostomy in place
  • Hemodynamic instability
  • Prolonged apnea
  • Inability to maintain the airway
  • A recent history of cardiac and or respiratory arrest
  • Acute hemorrhage
  • Multiple organ system failure
  • Undrained pneumothorax
  • High risk for aspiration
  • Metastatic or terminal cancer
  • Do-not-resuscitate orders
  • Inability to clear respiratory secretions
  • Inability to fit a mask
  • Facial surgery, trauma, or deformity
  • Upper gastrointestinal or airway surgery
  • +4 more criteria

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

GF-221 Health Sciences Centre

Winnipeg, Manitoba, R3E 0Z3, Canada

Location

MeSH Terms

Conditions

Respiratory Insufficiency

Condition Hierarchy (Ancestors)

Respiration DisordersRespiratory Tract Diseases

Study Officials

  • Steven Mink, MD

    University of Manitoba, Winnipeg, Manitoba, Canada

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Masking Details
Subject was blinded to device identity
Purpose
TREATMENT
Intervention Model
CROSSOVER
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

January 3, 2009

First Posted

January 6, 2009

Study Start

January 17, 2009

Primary Completion

March 3, 2009

Study Completion

April 7, 2009

Last Updated

November 17, 2017

Record last verified: 2017-04

Data Sharing

IPD Sharing
Will not share

Locations