NCT00816738

Brief Summary

To evaluate the clinical outcomes in patients with recurrent corneal erosions who received anterior stromal puncture by use of neodymium:yttrium-aluminum-garnet (Nd:YAG) laser.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
33

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started Jan 2008

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2008

Completed
1 month until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 1, 2008

Completed
29 days until next milestone

Study Completion

Last participant's last visit for all outcomes

March 1, 2008

Completed
6 months until next milestone

First Submitted

Initial submission to the registry

August 31, 2008

Completed
4 months until next milestone

First Posted

Study publicly available on registry

January 5, 2009

Completed
Last Updated

January 5, 2009

Status Verified

December 1, 2008

Enrollment Period

1 month

First QC Date

August 31, 2008

Last Update Submit

January 2, 2009

Conditions

Recurrent Corneal ErosionTrauma

Keywords

Nd: YAG laserrecurrent corneal erosionstraumaanterior stromal puncture

Outcome Measures

Primary Outcomes (1)

  • Cure rate of recurrent corneal erosions (frequency of attack and numbers of Nd: YAG laser treatment), intensity of pain relief and visual acuity.

    Before treatment, weekly after the treatment, and monthly after symptom relief

Eligibility Criteria

Age20 Years - 71 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

to evaluate the clinical outcomes after anterior stromal puncture with Nd:YAG laser in a consecutive series of 33 eyes in 33 patients with unilaterally recurrent corneal erosion.

You may qualify if:

  • patients with recurrent corneal erosions who showed poor response to conservative managements and were treated with Nd:YAG laser.

You may not qualify if:

  • Slit-lamp biomicroscopic examination in both eyes of patient showed any evidence of anterior basement membrane dystrophy.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

National Taiwan University Hospital

Taipei, 100, Taiwan

Location

MeSH Terms

Conditions

Wounds and Injuries

Study Officials

  • Yu-Chih Ho, MD

    National Taiwan University Hospital

    STUDY DIRECTOR

  • Tzu-Hsun Tsai, MD

    National Taiwan University Hospital

    PRINCIPAL INVESTIGATOR

  • Tzu-Yun Tsai, MD

    National Taiwan University Hospital

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER

Study Record Dates

First Submitted

August 31, 2008

First Posted

January 5, 2009

Study Start

January 1, 2008

Primary Completion

February 1, 2008

Study Completion

March 1, 2008

Last Updated

January 5, 2009

Record last verified: 2008-12

Locations

TW(1)