Fractional Exhaled Nitric Oxide (FeNO) Result Prediction Factors in Children With Allergic Diseases

NCT00815984 | Completed

• 1 other identifier: RNN/135/08/KE
• Study Type: observational
• Target: 800
• Locations: 1 country
• Sites: 1

Brief Summary

In about 800 children with allergic diseases (asthma, allergic rhinitis, atopic dermatitis) the investigators will retrospectively and cross-sectionally analyze the influence/correlation of diagnosis, treatment methods, allergy status (skin prick test results), lung function tests results on/with the concentration of nitric oxide in exhaled breath.

Conditions

Asthma; Allergic Rhinitis; Atopic Dermatitis

Keywords

Asthma; Allergic Rhinitis; Atopic Dermatitis; Children; lung function; skin prick tests; FeNO

Outcome Measures

Primary Outcomes (1)

• Concentration of nitric oxide in exhaled breath.

  1-4 months

Study Arms (1)

Schoolchildren with asthma.

Schoolchildren with asthma.

Procedure: measurements of lung function tests

Interventions

measurements of lung function tests PROCEDURE

Measurement of the concentration of FeNO , measurement of spirometry, plethysmography, exercise challenge test (ECT -spirometric), bronchial obstruction reversibility pharmacological test

Also known as: NO analyzer- Sievers 280i analyzer, Spirometry and Plethysmography - Jaeger, Exercise provocation test treadmill- Kettler

Schoolchildren with asthma.

Eligibility Criteria

• Age: 5 Years - 18 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64)
• Sampling Method: Probability Sample

Study Population

Children with asthma (allergic), and/or allergic rhinitis and/or atopic dermatitis

You may qualify if:

• Children with asthma (allergic), and/or allergic rhinitis and/or atopic dermatitis

You may not qualify if:

• Other chronic diseases
• Asthma exacerbation
• Pregnancy

Sponsors & Collaborators

• Medical University of Lodz: lead

Study Sites (1)

Department of Pediatrics and Allergy, N. Copernicus Hospital

Lodz, 93-513, Poland

Location

Related Publications (1)

• Grzelewski T, Majak P, Jerzynska J, Stelmach W, Stelmach R, Janas A, Grzelewska A, Witkowski K, Makandjou-Ola E, Stelmach I. The interpretation of exhaled nitric oxide values in children with asthma depends on the degree of bronchoconstriction and the levels of asthma severity. Respir Care. 2014 Sep;59(9):1404-11. doi: 10.4187/respcare.02889. Epub 2013 Dec 31.

  PMID: 24381190 DERIVED

MeSH Terms

Conditions

Asthma; Rhinitis, Allergic; Dermatitis, Atopic

Condition Hierarchy (Ancestors)

Bronchial Diseases; Respiratory Tract Diseases; Lung Diseases, Obstructive; Lung Diseases; Respiratory Hypersensitivity; Hypersensitivity, Immediate; Hypersensitivity; Immune System Diseases; Rhinitis; Nose Diseases; Otorhinolaryngologic Diseases; Skin Diseases, Genetic; Genetic Diseases, Inborn; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Dermatitis; Skin Diseases; Skin and Connective Tissue Diseases; Skin Diseases, Eczematous

Study Officials

• Iwona Stelmach, MD PhD Prof

  Department of Pediatrics and Allergy, N. Copernicus Hospital, Lodz, Poland

  STUDY CHAIR

• Tomasz Grzelewski, MD, PhD

  Department of Pediatrics and Allergy, N. Copernicus Hospital, Lodz, Poland

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER

Study Record Dates

• First Submitted: December 30, 2008
• First Posted: December 31, 2008
• Study Start: January 1, 2009
• Primary Completion: January 1, 2010
• Study Completion: January 1, 2010
• Last Updated: February 10, 2010

Record last verified: 2010-02

Locations

PL (1)