NCT00812500

Brief Summary

The purpose of this study was to assess the effect of age on the estimated average requirement and adequate allowance for dietary protein.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
48

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started May 2002

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

May 1, 2002

Completed
1 year until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 1, 2003

Completed
2.7 years until next milestone

Study Completion

Last participant's last visit for all outcomes

January 1, 2006

Completed
3 years until next milestone

First Submitted

Initial submission to the registry

December 18, 2008

Completed
4 days until next milestone

First Posted

Study publicly available on registry

December 22, 2008

Completed
Last Updated

September 24, 2013

Status Verified

December 1, 2008

Enrollment Period

1 year

First QC Date

December 18, 2008

Last Update Submit

September 23, 2013

Conditions

Keywords

assess the effect of age on the EAR and RDA for protein

Outcome Measures

Primary Outcomes (1)

  • To determine the dietary protein requirement of older men and women.

    57 days

Secondary Outcomes (1)

  • What is the lowest amount of protein that a man or women should eat each day to help him or her stay healthy?

    57 days

Study Arms (4)

1

EXPERIMENTAL

Young men, age 21-46 years.

Other: Lower ProteinOther: Medium ProteinOther: Higher Protein

2

EXPERIMENTAL

Old Men, age 63-81 years.

Other: Lower ProteinOther: Medium ProteinOther: Higher Protein

3

EXPERIMENTAL

Young women, age 21-46 years.

Other: Lower ProteinOther: Medium ProteinOther: Higher Protein

4

EXPERIMENTAL

Old women, age 63-81 years.

Other: Lower ProteinOther: Medium ProteinOther: Higher Protein

Interventions

Each subject completed an 18-day periods (trials) of strict dietary control of consuming a lower protein diet.

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Each subject completed an 18-day periods (trials) of strict dietary control of consuming a medium protein diet.

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Each subject completed an 18-day periods (trials) of strict dietary control of consuming a higher protein diet.

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Eligibility Criteria

Age18 Years - 85 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Age: 21-46 years, 63-81 years old
  • Not diagnosed with diabetes or metabolic syndrome
  • Clinically normal blood laboratory values

You may not qualify if:

  • Age: 21 years of younger, 47-62 years old, and 82 years and older
  • BMI: 20-29 kg/m
  • Weight stable: \<2kg change within the last 3 months
  • Physical Activity: constant habitual pattern, no deviation \>1x week of 30/minute sessions within the last 3 months
  • Clinically abnormal values:
  • Blood
  • Urine
  • Also, exclude any:
  • Using meds that would influence appetite
  • Using any anti-inflammatory steroid medications
  • Has a joint replacement
  • A medical condition that might place them at risk for participating in the study or interfere with successful completion of the study

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Purdue University

West Lafayette, Indiana, 47907, United States

Location

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Prof. Foods and Nutrition

Study Record Dates

First Submitted

December 18, 2008

First Posted

December 22, 2008

Study Start

May 1, 2002

Primary Completion

May 1, 2003

Study Completion

January 1, 2006

Last Updated

September 24, 2013

Record last verified: 2008-12

Locations