NCT00798824

Brief Summary

This clinical pilot trial is being conducted to learn more about the infant's feeding behavior while being fed by indwelling nasogastric tube placement or by intermittent oral tube placement. Healthy preterm infants who are transitioning from gavage to oral feedings via oral intermittent tube insertion may achieve full oral feeds by bottle/breast at an earlier gestational age than infants feeding with indwelling tubes and may be ready for earlier discharge.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
24

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Aug 2008

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

August 1, 2008

Completed
1 month until next milestone

First Submitted

Initial submission to the registry

September 12, 2008

Completed
3 months until next milestone

First Posted

Study publicly available on registry

November 26, 2008

Completed
1 year until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2009

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2009

Completed
Last Updated

October 13, 2010

Status Verified

October 1, 2010

Enrollment Period

1.3 years

First QC Date

September 12, 2008

Last Update Submit

October 12, 2010

Conditions

Keywords

tube feedingpremature infant

Outcome Measures

Primary Outcomes (1)

  • Gestational age of the last required tube feed.

    Last required tube feed

Secondary Outcomes (2)

  • Discharge date

    Discharge date

  • The amount suckled per day

    Discharge date

Study Arms (2)

Indwelling nasogastric tube placement

ACTIVE COMPARATOR
Procedure: Indwelling nasogastric tube placementDevice: Nasogastric tube

Intermittent orogastric tube placement

ACTIVE COMPARATOR
Procedure: Intermittent orogastric tube placementDevice: Oral gastric tube

Interventions

The premature infant is fed with an indwelling nasogastric tube during feeding transition.

Also known as: Nasogastric tube
Indwelling nasogastric tube placement

The premature infant is fed with an intermittently placed orogastric tube during feeding transition.

Also known as: Oral gastric tube
Intermittent orogastric tube placement

Premature infants will be fed with a nasogastric tube in place and their feeding behaviors will be noted till discharge.

Indwelling nasogastric tube placement

Premature infants will be fed with intermittent orogastric tube placement and their feeding behaviors will be noted till discharge.

Intermittent orogastric tube placement

Eligibility Criteria

Age30 Weeks - 33 Weeks
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17)

You may qualify if:

  • Premature infants born between 30-33 and 6/7th weeks gestation are an appropriate size for gestational age, are not on Oxygen are of any race, sex and require tube feeding and are less than 34 and 3/7th weeks gestation.

You may not qualify if:

  • infants with neurological abnormalities or insults, IVH greater than a grade of two, PVL, birth asphyxia, seizures, cord has less than 7.0 ph, chest compressions, infants who require abstinence scoring, infants with major congenital anomalies or major genetic anomalies that impact feeding ability such as diaphragmatic hernia and cleft palate, major cardiac defects, infants who develop necrotizing enterocolitis, infants who received more than 14 days of intubation or CPAP or oxygen by nasal prongs and infants of diabetic or alcoholic mothers.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Intermediate Care Unit, Health Sciences Centre

Winnipeg, Manitoba, Canada

Location

MeSH Terms

Conditions

Premature Birth

Interventions

Enteral Nutrition

Condition Hierarchy (Ancestors)

Obstetric Labor, PrematureObstetric Labor ComplicationsPregnancy ComplicationsFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital Diseases

Intervention Hierarchy (Ancestors)

Feeding MethodsTherapeuticsNutritional SupportNutrition Therapy

Study Officials

  • Judy A Kublick, Grad student

    University of Manitoba

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
SUPPORTIVE CARE
Intervention Model
PARALLEL
Sponsor Type
OTHER

Study Record Dates

First Submitted

September 12, 2008

First Posted

November 26, 2008

Study Start

August 1, 2008

Primary Completion

December 1, 2009

Study Completion

December 1, 2009

Last Updated

October 13, 2010

Record last verified: 2010-10

Locations