Misoprostol in Termination of First Trimester Missed Abortion
Oral Versus Vaginal Misoprostol as Cervical Ripening Agent Prior to Surgical Termination of First Trimester Missed Abortions in Hawler Maternity Teaching Hospital in Erbil/Iraq
1 other identifier
interventional
100
1 country
1
Brief Summary
The purpose of this study is to determine whether oral versus vaginal misoprostol is effective in termination of first trimester missed abortion and to compare between two different routes.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for not_applicable
Started Jan 2008
Shorter than P25 for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
January 1, 2008
CompletedPrimary Completion
Last participant's last visit for primary outcome
May 1, 2008
CompletedStudy Completion
Last participant's last visit for all outcomes
May 1, 2008
CompletedFirst Submitted
Initial submission to the registry
November 21, 2008
CompletedFirst Posted
Study publicly available on registry
November 25, 2008
CompletedNovember 25, 2008
November 1, 2008
4 months
November 21, 2008
November 24, 2008
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Priming with misoprostol administered orally or vaginally three hours before surgical termination of first trimester missed abortion under general anesthesia facilitates cervical dilatation
6 months
Secondary Outcomes (1)
Higher patient satisfaction for self administered oral misoprostol at home
6 months
Study Arms (2)
Vaginal Misoprostol
EXPERIMENTALA drug is given vaginally and to compare this with an oral administration of the same drug to find it is effect on it is effect on the cervix
Oral Misoprostol
EXPERIMENTALA drug is given vaginally and to compare this with an oral administration of the same drug to find it is effect on it is effect on the cervix
Interventions
In this study, two arms we put under study ... and to find how far a single drug, Misoprostol, is effective to have changes on the cervix.
Eligibility Criteria
You may qualify if:
- All patients were cases of first trimester missed abortion.
- They have uneventful history apart from history of slight vaginal bleeding, with normal general examination. Gynecological examination revealed no vaginal bleeding or discharge with no dilatation of the internal os with enlarged uterus.
You may not qualify if:
- Cases with suspected or proven ectopic pregnancy, history of Caesarean section, medical diseases, a known hypersensitivity to a drug, smokers, patients with abnormal results of investigation and the presence of vaginal bleeding were excluded from the study.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Hawler Medical Universitylead
- HAWLER Maternity Hospitalcollaborator
Study Sites (1)
Maternity Teaching Hospital
Erbil, Hawler, 964, Iraq
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- NONE
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
Study Record Dates
First Submitted
November 21, 2008
First Posted
November 25, 2008
Study Start
January 1, 2008
Primary Completion
May 1, 2008
Study Completion
May 1, 2008
Last Updated
November 25, 2008
Record last verified: 2008-11