NCT00786773

Brief Summary

To describe the change of impact of reflux symptoms on the everyday life perceived by patients before and after 4 weeks treatment by using GERD Impact Scale questionnaire (GIS) by total GERD patient population and by treatment group; and to describe the concordance between patient-reported and physician-reported symptom load.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
2,091

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Oct 2008

Shorter than P25 for all trials

Geographic Reach
1 country

18 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 1, 2008

Completed
1 month until next milestone

First Submitted

Initial submission to the registry

November 5, 2008

Completed
1 day until next milestone

First Posted

Study publicly available on registry

November 6, 2008

Completed
7 months until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2009

Completed
Last Updated

December 7, 2010

Status Verified

December 1, 2010

First QC Date

November 5, 2008

Last Update Submit

December 6, 2010

Conditions

Keywords

GERDreflux symptomheartburnacid regurgitationPPIH2RAantacid

Outcome Measures

Primary Outcomes (1)

  • Type, frequency and severity of the GERD symptoms

    4 weeks

Study Arms (1)

1

GERD patients who will be treated for GERD with PPI, H2RA, antacid, prokinetics, combination therapy

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

The target survey population is existing GERD patients or newly diagnosed GERD patients, who will be treated for GERD with PPI, H2RA, antacid, prokinetics, combination therapy ... at Visit 1 and will come back after 4 weeks for clinical re-assessment (Visit 2)

You may qualify if:

  • Patients with GERD diagnosed clinically or by endoscopy and prescribed with medical treatments
  • Provision of written informed consent

You may not qualify if:

  • Patients cannot read and/or understand GIS
  • Patients with the history or symptoms of peptic ulcer, gastrointestinal cancer, serious or malignant diseases (anorexia, weight loss, anemia, fever …)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (18)

Research Site

Long Xuyen, An Giang, Vietnam

Location

Research Site

Qui Nhon, Binh Dinh, Vietnam

Location

Research Site

Buon Ma Thuot, Dac Lac, Vietnam

Location

Research Site

Biên Hòa, Dong Nai, Vietnam

Location

Research Site

Thống Nhất, Dong Nai, Vietnam

Location

Research Site

Cao Lanh, Dong Thap, Vietnam

Location

Research Site

Sa Dec, Dong Thap, Vietnam

Location

Research Site

Nha Trang, Khanh Hoa, Vietnam

Location

Research Site

Huế, Thừa Thiên Huế Province, Vietnam

Location

Research Site

Can Tho, Vietnam

Location

Research Site

Cà Mau, Vietnam

Location

Research Site

Da Nang, Vietnam

Location

Research Site

Haiphong, Vietnam

Location

Research Site

Hanoi, Vietnam

Location

Research Site

Ho Chi Minh City, Vietnam

Location

Research Site

Mỹ Tho, Vietnam

Location

Research Site

Nam Định, Vietnam

Location

Research Site

Thái Bình, Vietnam

Location

MeSH Terms

Conditions

Gastroesophageal RefluxHeartburn

Condition Hierarchy (Ancestors)

Esophageal Motility DisordersDeglutition DisordersEsophageal DiseasesGastrointestinal DiseasesDigestive System DiseasesSigns and Symptoms, DigestiveSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Officials

  • Ta Long

    Vietnam Association of Gastroenterology

    PRINCIPAL INVESTIGATOR
  • Dao Van Long

    Medical University of Hanoi

    PRINCIPAL INVESTIGATOR
  • Tran Kieu Mien

    HCMC Association of Gastroenterology

    PRINCIPAL INVESTIGATOR
  • Le Thanh Ly

    Cho Ray Hospital

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Time Perspective
PROSPECTIVE
Sponsor Type
INDUSTRY

Study Record Dates

First Submitted

November 5, 2008

First Posted

November 6, 2008

Study Start

October 1, 2008

Study Completion

June 1, 2009

Last Updated

December 7, 2010

Record last verified: 2010-12

Locations