Postpartum Anemia and Postpartum Depression
PPADS
Is Postpartum Anemia an Independent Risk Factor for Development of Postpartum Depression?
1 other identifier
observational
103
1 country
1
Brief Summary
Postpartum anemia (PPA) and Postpartum depression (PPD) are common afflictions affecting women after childbirth. Both disorders have a significant impact on women's health and functional status. Despite common symptoms and characteristics, a link between these entities has not been adequately studied. The objective of this study is to determine whether postpartum anemia is an independent risk factor for the development of postpartum depression. This prospective cohort study will include all women delivered by elective term cesarean delivery. Hemoglobin and iron levels will be measured, standardized questionnaires for assessment of PPD, functional status and lactation will be administered before discharge and at 3 \& 6 weeks post partum. Hemoglobin levels at each time point will be analyzed for correlation with depressive symptoms, functional status and lactation success.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for all trials
Started Nov 2008
Longer than P75 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
October 30, 2008
CompletedFirst Posted
Study publicly available on registry
October 31, 2008
CompletedStudy Start
First participant enrolled
November 1, 2008
CompletedPrimary Completion
Last participant's last visit for primary outcome
October 1, 2014
CompletedStudy Completion
Last participant's last visit for all outcomes
October 1, 2014
CompletedFebruary 22, 2019
February 1, 2019
5.9 years
October 30, 2008
February 20, 2019
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Incidence of postpartum depression
0-6 weeks postpartum
Secondary Outcomes (3)
Mean Edinburgh Postnatal Depression Scale results
0-6 weeks postpartum
Functional status
0-6 weeks postpartum
Lactation success
0-6 weeks postpartum
Eligibility Criteria
Women after term elective cesarean section
You may qualify if:
- Women after term elective cesarean section
You may not qualify if:
- age \< 16 years, preterm (\< 37 weeks) delivery, multiple gestation, symptomatic anemia necessitating blood transfusion, significant fetal anomalies or infant not discharged with mother for other reason, preexisting severe chronic maternal illness, preexisting maternal depression and/or current use of antidepressants, other psychiatric illness (e.g. bipolar disease, schizophrenia) or preexisting hemoglobinopathy
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
St. Michael's Hospital
Toronto, Ontario, M5B1W8, Canada
Biospecimen
Blood samples
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Howard Berger, MD
Unity Health Toronto
Study Design
- Study Type
- observational
- Observational Model
- CASE CONTROL
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
October 30, 2008
First Posted
October 31, 2008
Study Start
November 1, 2008
Primary Completion
October 1, 2014
Study Completion
October 1, 2014
Last Updated
February 22, 2019
Record last verified: 2019-02