NCT00782314

Brief Summary

We want to evaluate efficacy of Symbicort® Turbuhaler® (formoterol/budesonide) therapy for asthma in real life conditions. For this purpose we will include both patients that are treated with Symbicort® Turbuhaler® the "classical" maintenance only treatment approach as well as those treated with the SMART approach.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
400

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Apr 2008

Shorter than P25 for all trials

Geographic Reach
1 country

24 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

April 1, 2008

Completed
7 months until next milestone

First Submitted

Initial submission to the registry

October 29, 2008

Completed
2 days until next milestone

First Posted

Study publicly available on registry

October 31, 2008

Completed
5 months until next milestone

Study Completion

Last participant's last visit for all outcomes

April 1, 2009

Completed
Last Updated

July 24, 2009

Status Verified

July 1, 2009

First QC Date

October 29, 2008

Last Update Submit

July 23, 2009

Conditions

Keywords

asthmaSMARTSymbicort Turbuhalerasthma control

Outcome Measures

Primary Outcomes (1)

  • to determine the efficacy of both possible treatment approaches with Symbicort® Turbuhaler®, measured by asthma control

    three times: 0, 3, 6 months after inclusion

Secondary Outcomes (1)

  • to determine the number of maintenance and reliever inhalations of Symbicort® Turbuhaler®, as well as the concomitant usage of a separate reliever inhaler even in the case of SMART treatment approach

    three times: 0, 3, 6 months after inclusion

Study Arms (2)

1

patients with maintenance only treatment with Symbicort Turbuhaler for at least 1 month

2

patients with SMART treatment with Symbicort Turbuhaler for at least 1 month

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

patients visiting pulmologist's office

You may qualify if:

  • patients diagnosed with persistent asthma treated with Symbicort® Turbuhaler® in line with its label
  • non-pregnant females
  • existing maintenance only treatment with Symbicort® Turbuhaler® 80 μg/4,5 μg, 160 μg/4,5 μg or 320 μg/9 μg for at least 1 month
  • existing SMART treatment with Symbicort® Turbuhaler® 80 μg/4,5 μg or 160 μg /4,5 μg for at least 1 month

You may not qualify if:

  • patients not being treated with Symbicort® Turbuhaler®
  • patients treated with Symbicort® Turbuhaler® for COPD

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (24)

Research Site

Celje, Celje, Slovenia

Location

Research Site

Dvorec Sela, Dvorec Sela, Slovenia

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Research Site

Grosuplje, Grosuplje, Slovenia

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Idrija, Idrija, Slovenia

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Izola, Izola, Slovenia

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Jesenice, Jesenice, Slovenia

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Kamnik-Duplica, Kamnik-Duplica, Slovenia

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Kranj, Kranj, Slovenia

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Litija, Litija, Slovenia

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Ljubljana, Ljubljana, Slovenia

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Lucija, Lucija, Slovenia

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Maribor, Maribor City Municipality, Slovenia

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Novo Mesto, Mestna Občina Novo mesto, Slovenia

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Murska Sobota, Murska Sobota, Slovenia

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Domžale, Občina Domžale, Slovenia

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Ravne na Koroškem, Občina Ravne na Koroškem, Slovenia

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Sežana, Občina Sežana, Slovenia

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Ptuja, Ptuja, Slovenia

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Slovenj Gradec, Slovenj Gradec, Slovenia

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Slovenska Bistrica, Slovenska Bistrica, Slovenia

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Topolšica, Topolsica, Slovenia

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Velenje, Velenje, Slovenia

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Vrhnika, Vrhnika, Slovenia

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Research Site

Zagorje, Zagorje, Slovenia

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MeSH Terms

Conditions

Asthma

Condition Hierarchy (Ancestors)

Bronchial DiseasesRespiratory Tract DiseasesLung Diseases, ObstructiveLung DiseasesRespiratory HypersensitivityHypersensitivity, ImmediateHypersensitivityImmune System Diseases

Study Officials

  • Igor Koren, MD, MSc

    Radix - medicinske storitve, Igor Koren s.p.

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
CASE CONTROL
Time Perspective
PROSPECTIVE
Sponsor Type
INDUSTRY

Study Record Dates

First Submitted

October 29, 2008

First Posted

October 31, 2008

Study Start

April 1, 2008

Study Completion

April 1, 2009

Last Updated

July 24, 2009

Record last verified: 2009-07

Locations