NCT00780936

Brief Summary

The purpose of this study is to determine the effect of a local anesthetic nerve block on markers of inflammation and pain after a sunburn. This is important because it may provide information regarding the way that nerve blocks help with the treatment of pain and in particular provide preemptive analgesia.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
15

participants targeted

Target at below P25 for not_applicable pain

Timeline
Completed

Started Oct 2007

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 1, 2007

Completed
9 months until next milestone

Study Completion

Last participant's last visit for all outcomes

July 1, 2008

Completed
4 months until next milestone

First Submitted

Initial submission to the registry

October 24, 2008

Completed
4 days until next milestone

First Posted

Study publicly available on registry

October 28, 2008

Completed
Last Updated

November 24, 2008

Status Verified

November 1, 2008

First QC Date

October 24, 2008

Last Update Submit

November 21, 2008

Conditions

Pain

Outcome Measures

Primary Outcomes (1)

  • Measurement of the effect of a preemptive peripheral nerve block on the hyperalgesic response to an artificially induced sunburn.

Secondary Outcomes (1)

  • Measurement of the effect of a preemptive peripheral nerve block on the release of pro-inflammatory cytokines.

Interventions

femoral nerve blockPROCEDURE

Eligibility Criteria

Age18 Years - 50 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Stanford University School of Medicine

Stanford, California, 94305, United States

Location

MeSH Terms

Conditions

Pain

Condition Hierarchy (Ancestors)

Neurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Officials

  • Martin S Angst

    Stanford University

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Purpose
PREVENTION
Intervention Model
CROSSOVER
Sponsor Type
OTHER

Study Record Dates

First Submitted

October 24, 2008

First Posted

October 28, 2008

Study Start

October 1, 2007

Study Completion

July 1, 2008

Last Updated

November 24, 2008

Record last verified: 2008-11

Locations

US(1)