Conditioning Regimen Before Infusion of Allogeneic Hematopoietic Stem Cells
Unrelated Donor Hematopoietic Stem Cell Transplantation After Nonmyeloablative Conditioning for Younger Patients With Hematologic Malignancies
1 other identifier
observational
52
1 country
1
Brief Summary
Unrelated Donor Hematopoietic Stem Cell Transplantation After Nonmyeloablative Conditioning for Younger Patients with Hematologic Malignancies.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for all trials
Started Dec 2003
Longer than P75 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
December 1, 2003
CompletedPrimary Completion
Last participant's last visit for primary outcome
March 1, 2008
CompletedFirst Submitted
Initial submission to the registry
October 5, 2008
CompletedFirst Posted
Study publicly available on registry
October 10, 2008
CompletedStudy Completion
Last participant's last visit for all outcomes
December 1, 2008
CompletedJune 10, 2011
June 1, 2011
4.3 years
October 5, 2008
June 8, 2011
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
treatment-related mortality and engraftment
all cause mortality
Secondary Outcomes (1)
regimen-related toxicities, graft-versus-host-disease, relapse, and overall survival.
Time point(s) at which outcome measure is assessed.
Eligibility Criteria
acute leukemia chronic myelogenous leukemia myelodysplastic syndrome
You may qualify if:
- Patients should have an unrelated donor who is matched for HLA-A and -B by serology and for -DRB1 by molecular typing.
You may not qualify if:
- Patients should not have major illness or organ failure
- Patients must not have a psychiatric disorder or mental deficiency severe as to make compliance with the treatment unlike, and making informed consent impossible.
- Patients must not be pregnant or lactating.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Asan Medical Center
Seoul, 138-736, South Korea
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Kyoo-hyung Lee, doctor
COSAH
Study Design
- Study Type
- observational
- Observational Model
- CASE ONLY
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- NETWORK
Study Record Dates
First Submitted
October 5, 2008
First Posted
October 10, 2008
Study Start
December 1, 2003
Primary Completion
March 1, 2008
Study Completion
December 1, 2008
Last Updated
June 10, 2011
Record last verified: 2011-06