Study of the Human Skin Microbiome

NCT00764608 | Withdrawn DMC

• 1 other identifier: 56-RW-012
• Study Type: observational
• Target: N/A
• Locations: 1 country
• Sites: 1

Brief Summary

Numerous organisms live on and in healthy human skin. This study seeks to survey the diversity of this complex ecosystem by collecting samples from approximately 1000 individuals in order to determine the type of organisms living on their skin.

Conditions

Healthy

Outcome Measures

Primary Outcomes (1)

• Numerous organisms live on and in healthy human skin. This study seeks to survey the diversity of this complex ecosystem by collecting samples from approximately 1000 individuals in order to determine the type of organisms living on their skin.

  2 years

Study Arms (1)

No Treatment

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

It is the goal of the study to survey multiple skin locations of humans at multiple time points

You may qualify if:

• Subjects must be 18 years of age or older.
• Subjects must be able to consent for themselves.
• Must be willing to participate to a swab of the skin.

You may not qualify if:

• Subjects cannot be 17 years of age or younger.

Sponsors & Collaborators

• Southwest Regional Wound Care Center: lead

Study Sites (1)

Southwest Regional Wound Care Center

Lubbock, Texas, 79410, United States

Location

Biospecimen

Retention: SAMPLES WITH DNA

The subjects' samples will be analyzed using DNA methods in order to identify the types of microbes present on the swabs. Other substances such as proteins, RNA, and other metabolites may also be analyzed. DNA or other molecular components of the sample will be extracted. Alternately, microbes in the sample can be cultured directly. The samples will be explored using molecular analyses. The backbone of the analyses will be shotgun metagenomic sequencing and 16S rDNA amplicon sequencing. The results of these analyses will be used to identify and describe the microbiome of the skin.

Study Officials

• Randall Wolcott, MD

  Southwest Regional Wound Care Center

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Prinicipal Investigator

Study Record Dates

• First Submitted: September 30, 2008
• First Posted: October 2, 2008
• Study Start: June 1, 2008
• Primary Completion: February 1, 2009
• Study Completion: February 1, 2009
• Last Updated: November 26, 2015

Record last verified: 2015-11

Locations

US (1)