Measurement of Cardiac Output and Blood Volumes Using Transonic Ultrasound Dilution Technology

NCT00756119 | Completed

• 1 other identifier: TSI-R-COstatus-1A-H
• Study Type: observational
• Target: 26
• Locations: 1 country
• Sites: 1

Brief Summary

Measurement of the amount of blood pumped by the heart (cardiac output) and blood volumes in sick patients is important for doctors to better treat these patients. Current procedures available demand difficult invasive procedures and hence these parameters are not measured with enough frequency and are also limited to certain patients. The new COstatus system is capable of using the already existing arterial and venous lines placed in critically ill patients and thus provides an opportunity to measure these parameters less invasively and with enough frequency. The purpose of this study is to measure cardiac output and blood volumes using ultrasound dilution technology (COstatus system)in post cardiac surgery adult patients and compare the cardiac output measurements with a current clinical reference method, thermodilution.

Conditions

Post Cardiac Surgery Patients

Eligibility Criteria

• Age: 21 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Post cardiac surgery adult patients

You may qualify if:

• Post cardiac surgery adult patients
• Patients with heart catheter and arterial catheter

Sponsors & Collaborators

• Transonic Systems Inc.: lead
• Russian Academy of Medical Sciences: collaborator

Study Sites (1)

National Research Center of Surgery, Russian Academy of Medical Sciences

Moscow, Moscow, 119992, Russia

Location

Related Publications (3)

• Eremenko A, Balykov I, Chaus N, Kislukhin V, Krivitski N. Use of an extracorporeal arteriovenous tubing loop to measure cardiac output in intensive care unit patients by ultrasound velocity dilution. ASAIO J. 1998 Sep-Oct;44(5):M462-4. doi: 10.1097/00002480-199809000-00028.

  PMID: 9804473 BACKGROUND

• Eremenko AA, Chaus NI, Kislukhin VV, Balykov IV. [The determination of cardiac output by the dilution of ultrasonic blood density]. Anesteziol Reanimatol. 1998 Jul-Aug;(4):4-6. Russian.

  PMID: 9770808 BACKGROUND

• Krivitski NM, Kislukhin VV, Thuramalla NV. Theory and in vitro validation of a new extracorporeal arteriovenous loop approach for hemodynamic assessment in pediatric and neonatal intensive care unit patients. Pediatr Crit Care Med. 2008 Jul;9(4):423-8. doi: 10.1097/01.PCC.0b013e31816c71bc.

  PMID: 18496416 BACKGROUND

Study Officials

• Alexsandr A Eremenko, MD

  Russian Academy of Medical Sciences

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: PROSPECTIVE
• Sponsor Type: INDUSTRY
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: September 17, 2008
• First Posted: September 19, 2008
• Study Start: December 1, 2006
• Primary Completion: December 1, 2009
• Study Completion: December 1, 2009
• Last Updated: May 31, 2012

Record last verified: 2012-05

Locations

RU (1)