NCT00749762

Brief Summary

This study seeks to determine in Neonatal Intensive Care Unit (NICU) patients specific improvements in pulmonary function which may occur when an infant is ventilated in the prone as compared to the supine position. Modest improvement in oxygen has been reported to occur with prone positioning, but the exact etiology for this change is not clear. A special incubator designed as an integrated care system allows routine care and the measurement of both patient and ventilator breaths during mechanical ventilation. This study will utilize this device to evaluate in NICU ventilated patients whether specific changes in pulmonary function accompany position changes, and whether these are correlated to a change in pulmonary gas exchange.

Trial Health

30
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Timeline
Completed

Started Oct 2002

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
withdrawn

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 1, 2002

Completed
5.9 years until next milestone

First Submitted

Initial submission to the registry

September 8, 2008

Completed
1 day until next milestone

First Posted

Study publicly available on registry

September 9, 2008

Completed
1.6 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 1, 2010

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

May 1, 2010

Completed
Last Updated

May 5, 2015

Status Verified

May 1, 2010

Enrollment Period

7.6 years

First QC Date

September 8, 2008

Last Update Submit

May 1, 2015

Conditions

Keywords

DURINGPRONESUPINEPOSITIONING

Eligibility Criteria

Age24 Hours - 6 Months
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17)
Sampling MethodNon-Probability Sample
Study Population

For stable NICU infants who require assisted mechanical ventilation beginning after the 1st 24 hours of life and repeating every 2 to 7 days

You may qualify if:

  • Any NICU patient who does not have a major congenital anomaly and is on assisted mechanical ventilation will be eligible for this study.

You may not qualify if:

  • Healthy patients

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Utah / Primary Childrens Medical Center

Salt Lake City, Utah, 84132, United States

Location

MeSH Terms

Conditions

Deception

Condition Hierarchy (Ancestors)

Social BehaviorBehavior

Study Officials

  • Donald .Null, M.D.

    University of Utah

    PRINCIPAL INVESTIGATOR
0

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER

Study Record Dates

First Submitted

September 8, 2008

First Posted

September 9, 2008

Study Start

October 1, 2002

Primary Completion

May 1, 2010

Study Completion

May 1, 2010

Last Updated

May 5, 2015

Record last verified: 2010-05

Locations