NCT00746161

Brief Summary

The purpose of this study is to evaluate the double tract reconstruction after total gastrectomy in patients with gastric cancer. A prospective randomized controlled trial was conducted to compare double tract method with Roux-en-Y method

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
44

participants targeted

Target at below P25 for phase_3 gastric-cancer

Timeline
Completed

Started Apr 2002

Typical duration for phase_3 gastric-cancer

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

April 1, 2002

Completed
5.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 1, 2008

Completed
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

April 1, 2008

Completed
5 months until next milestone

First Submitted

Initial submission to the registry

September 2, 2008

Completed
1 day until next milestone

First Posted

Study publicly available on registry

September 3, 2008

Completed
Last Updated

September 4, 2008

Status Verified

September 1, 2008

Enrollment Period

5.8 years

First QC Date

September 2, 2008

Last Update Submit

September 3, 2008

Conditions

Keywords

total gastrectomydouble tract reconstructiongastric cancerTotal gastrectomy in patients with gastric cancer

Outcome Measures

Primary Outcomes (1)

  • The %body weight ratio

    12 months after operation

Secondary Outcomes (1)

  • preoperative complication, PNI and QOL score

    within one month, and 3 and 12months after operation

Study Arms (2)

1

ACTIVE COMPARATOR

Roux-en-Y

Procedure: Reconstruction after total gastrectomy

2

EXPERIMENTAL

double tract reconstruction

Procedure: Reconstruction after total gastrectomy

Interventions

Eligibility Criteria

AgeUp to 80 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • Histologically proven adenocarcinoma without esophageal invasion, tumor status T1-2
  • Age 80 years or younger
  • No distant metastasis

You may not qualify if:

  • Carcinoma in the remnant stomach
  • Stage intravenous (IV)
  • History of laparotomy
  • History of serious heart disease
  • Liver cirrhosis or chronic liver disease with indocyanine green excretion test at 15 min of 15% or more
  • Absence of informed consent

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Second Department of Surgery, Wakayama Medical University

Wakayama, Wakayama, 641-8510, Japan

Location

Related Publications (1)

  • Iwahashi M, Nakamori M, Nakamura M, Naka T, Ojima T, Iida T, Katsuda M, Ueda K, Yamaue H. Evaluation of double tract reconstruction after total gastrectomy in patients with gastric cancer: prospective randomized controlled trial. World J Surg. 2009 Sep;33(9):1882-8. doi: 10.1007/s00268-009-0109-0.

MeSH Terms

Conditions

Stomach Neoplasms

Condition Hierarchy (Ancestors)

Gastrointestinal NeoplasmsDigestive System NeoplasmsNeoplasms by SiteNeoplasmsDigestive System DiseasesGastrointestinal DiseasesStomach Diseases

Study Officials

  • Makoto Iwahashi

    Second Department of Surgery, Wakayama Medical University

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
phase 3
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER

Study Record Dates

First Submitted

September 2, 2008

First Posted

September 3, 2008

Study Start

April 1, 2002

Primary Completion

January 1, 2008

Study Completion

April 1, 2008

Last Updated

September 4, 2008

Record last verified: 2008-09

Locations