NCT00744094

Brief Summary

In the present study the investigators aim to determine whether protein supplementation can augment the response to a 12 week resistance training program in healthy elderly men.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
26

participants targeted

Target at P25-P50 for phase_1

Timeline
Completed

Started Jan 2007

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2007

Completed
8 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 1, 2007

Completed
10 months until next milestone

Study Completion

Last participant's last visit for all outcomes

July 1, 2008

Completed
2 months until next milestone

First Submitted

Initial submission to the registry

August 28, 2008

Completed
1 day until next milestone

First Posted

Study publicly available on registry

August 29, 2008

Completed
Last Updated

September 23, 2015

Status Verified

August 1, 2008

Enrollment Period

8 months

First QC Date

August 28, 2008

Last Update Submit

September 22, 2015

Conditions

SarcopeniaAtrophyAging

Keywords

resistance trainingprotein supplementationhypertrophy

Outcome Measures

Primary Outcomes (1)

  • Muscle mass measured at limb and cellular level

    before and after 12 weeks of intervention

Secondary Outcomes (2)

  • Muscle strength

    before and after 12 weeks of intervention

  • Body composition

    before and after 12 weeks of intervention

Study Arms (2)

1

PLACEBO COMPARATOR

placebo drink

Behavioral: Resistance training

2

EXPERIMENTAL

protein drink

Dietary Supplement: protein drinkBehavioral: Resistance training

Interventions

protein drinkDIETARY_SUPPLEMENT

250 ml protein hydrolysate solution

2
Resistance trainingBEHAVIORAL

12 weeks resistance training, 3 days per week

12

Eligibility Criteria

Age65 Years - 85 Years
Sexmale
Healthy VolunteersYes
Age GroupsOlder Adult (65+)

You may qualify if:

  • Living independently

You may not qualify if:

  • Diabetes
  • Cardiovascular disease
  • Orthopedic limitations
  • Any disorder known to compromise ability for resistance training
  • History of resistance training in past 5 years

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Maastricht University

Maastricht, 6200MD, Netherlands

Location

Related Publications (1)

  • Verdijk LB, Jonkers RA, Gleeson BG, Beelen M, Meijer K, Savelberg HH, Wodzig WK, Dendale P, van Loon LJ. Protein supplementation before and after exercise does not further augment skeletal muscle hypertrophy after resistance training in elderly men. Am J Clin Nutr. 2009 Feb;89(2):608-16. doi: 10.3945/ajcn.2008.26626. Epub 2008 Dec 23.

    PMID: 19106243DERIVED

MeSH Terms

Conditions

SarcopeniaAtrophyHypertrophy

Interventions

Resistance Training

Condition Hierarchy (Ancestors)

Muscular AtrophyNeuromuscular ManifestationsNeurologic ManifestationsNervous System DiseasesPathological Conditions, AnatomicalPathological Conditions, Signs and SymptomsSigns and Symptoms

Intervention Hierarchy (Ancestors)

Exercise TherapyRehabilitationAftercareContinuity of Patient CarePatient CareTherapeuticsPhysical Therapy ModalitiesPhysical Conditioning, HumanExerciseMotor ActivityMovementMusculoskeletal Physiological PhenomenaMusculoskeletal and Neural Physiological Phenomena

Study Officials

  • Luc JC van Loon, PhD

    Maastricht University

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
phase 1
Allocation
RANDOMIZED
Masking
TRIPLE
Who Masked
PARTICIPANT, INVESTIGATOR, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER

Study Record Dates

First Submitted

August 28, 2008

First Posted

August 29, 2008

Study Start

January 1, 2007

Primary Completion

September 1, 2007

Study Completion

July 1, 2008

Last Updated

September 23, 2015

Record last verified: 2008-08

Locations

NL(1)