NCT00740480

Brief Summary

The purpose of this research study is to learn more about the ENTact™ Septal Staple System device performance and to collect information to support its premarket application.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
25

participants targeted

Target at below P25 for all trials

Timeline
Completed

Started Apr 2008

Shorter than P25 for all trials

Geographic Reach
1 country

3 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

April 1, 2008

Completed
5 months until next milestone

First Submitted

Initial submission to the registry

August 21, 2008

Completed
4 days until next milestone

First Posted

Study publicly available on registry

August 25, 2008

Completed
5 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 1, 2009

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

February 1, 2009

Completed
7 months until next milestone

Results Posted

Study results publicly available

August 21, 2009

Completed
Last Updated

August 25, 2009

Status Verified

August 1, 2009

Enrollment Period

10 months

First QC Date

August 21, 2008

Results QC Date

July 15, 2009

Last Update Submit

August 20, 2009

Conditions

Keywords

EvaluationENTact™SeptalStapleSystemtissueapproximationduringseptoplasties

Outcome Measures

Primary Outcomes (1)

  • Coaptation (Tissue Approximation)

    Complete tissue approximation at one week.

    One week post surgery

Secondary Outcomes (1)

  • Tissue Reaction to Implant

    One week post surgery

Study Arms (1)

Surgical

Adult population (ages 18-65) with clinically significant nasal septum deviation.

Eligibility Criteria

Age18 Years - 65 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Adult patients (ages 18-65) with clinically significant nasal septum deviation.

You may qualify if:

  • Adult patients, between the ages of 18 and 65 years, with a clinically significant deviation of the nasal septum
  • Patient is able to provide a signed informed consent form
  • Patient will agree to comply with all study related procedures
  • Patient is not pregnant at this time. If patient is of child-bearing age and capable of bearing children, a pre-operative pregnancy test confirmation is required to show that patient is not pregnant on the day of surgery
  • Patient does not plan on becoming pregnant and is not breast feeding during the course of the study

You may not qualify if:

  • Patients who have had previous septoplasty
  • Patients with uncontrolled diabetes
  • Presence of infection at the site
  • Smokers and severe drug and alcohol abusers
  • Patients with autoimmune disease deemed clinically significant by Principal Investigator

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (3)

Good Samaritan Hospital

Cincinnati, Ohio, 45220, United States

Location

Park Hudson Surgery Center

Bryan, Texas, 77802, United States

Location

Physician's Ambulatory Surgery Center IV

San Antonio, Texas, 78258, United States

Location

Results Point of Contact

Title
Gabriele Niederauer, PhD
Organization
ENTrigue Surgical, Inc.

Study Officials

  • Gabriele G Niederauer, Ph.D.

    ENTrigue Surgical, Inc.

    STUDY DIRECTOR

Publication Agreements

PI is Sponsor Employee
No
Restrictive Agreement
No

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
PROSPECTIVE
Sponsor Type
INDUSTRY

Study Record Dates

First Submitted

August 21, 2008

First Posted

August 25, 2008

Study Start

April 1, 2008

Primary Completion

February 1, 2009

Study Completion

February 1, 2009

Last Updated

August 25, 2009

Results First Posted

August 21, 2009

Record last verified: 2009-08

Locations