NCT00736502

Brief Summary

The aim of this trial is to evaluate the safety and virological and immunological efficacy of Viramune® on a background of different antiretroviral drug combinations.

Trial Health

85
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
280

participants targeted

Target at P75+ for all trials

Geographic Reach
2 countries

17 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

July 7, 2008

Completed
1 month until next milestone

First Posted

Study publicly available on registry

August 18, 2008

Completed
14 days until next milestone

Study Start

First participant enrolled

September 1, 2008

Completed
2.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 1, 2011

Completed
1.2 years until next milestone

Results Posted

Study results publicly available

August 31, 2012

Completed
Last Updated

March 7, 2014

Status Verified

February 1, 2014

Enrollment Period

2.8 years

First QC Date

July 7, 2008

Results QC Date

July 30, 2012

Last Update Submit

February 3, 2014

Conditions

Outcome Measures

Primary Outcomes (1)

  • Proportion of Patients Reporting Adverse Events

    the incidence of non serious adverse events and serious adverse events according to body system (= System Organ Class) and preferred term.

    48 weeks

Secondary Outcomes (2)

  • Virologic Response (VR)

    48 weeks

  • Change in CD4+ Cell Count From Baseline to Week 48

    Baseline and week 48

Study Arms (1)

Patients HIV-1 positive

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

patients

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (17)

Boehringer Ingelheim Investigational Site 1

Graz, Austria

Location

Boehringer Ingelheim Investigational Site 2

Linz, Austria

Location

Boehringer Ingelheim Investigational Site 3

Salzburg, Austria

Location

Boehringer Ingelheim Investigational Site 4

Vienna, Austria

Location

Boehringer Ingelheim Investigational Site 5

Vienna, Austria

Location

Boehringer Ingelheim Investigational Site 6

Vienna, Austria

Location

Boehringer Ingelheim Investigational Site 7

Wels, Austria

Location

Boehringer Ingelheim Investigational Site 8

Bialystok, Poland

Location

Boehringer Ingelheim Investigational Site 9

Bydgoszcz, Poland

Location

Boehringer Ingelheim Investigational Site 10

Chorzów, Poland

Location

Boehringer Ingelheim Investigational Site 11

Gdansk, Poland

Location

Boehringer Ingelheim Investigational Site 12

Krakow, Poland

Location

Boehringer Ingelheim Investigational Site 13

Lódz, Poland

Location

Boehringer Ingelheim Investigational Site 14

Poznan, Poland

Location

Boehringer Ingelheim Investigational Site 15

Szczecin, Poland

Location

Boehringer Ingelheim Investigational Site 16

Warsaw, Poland

Location

Boehringer Ingelheim Investigational Site 17

Wroclaw, Poland

Location

MeSH Terms

Conditions

HIV Infections

Condition Hierarchy (Ancestors)

Blood-Borne InfectionsCommunicable DiseasesInfectionsSexually Transmitted Diseases, ViralSexually Transmitted DiseasesLentivirus InfectionsRetroviridae InfectionsRNA Virus InfectionsVirus DiseasesGenital DiseasesUrogenital DiseasesImmunologic Deficiency SyndromesImmune System Diseases

Results Point of Contact

Title
Boehringer Ingelheim Call Center
Organization
Boehringer Ingelheim Pharmaceuticals

Study Officials

  • Boehringer Ingelheim

    Boehringer Ingelheim

    STUDY CHAIR

Publication Agreements

PI is Sponsor Employee
No
Restriction Type
OTHER
Restrictive Agreement
Yes

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

July 7, 2008

First Posted

August 18, 2008

Study Start

September 1, 2008

Primary Completion

July 1, 2011

Last Updated

March 7, 2014

Results First Posted

August 31, 2012

Record last verified: 2014-02

Locations