The Effects of Home-Based Rehabilitation Treatments Among Persons With Symptomatic Knee Osteoarthritis

NCT00735098 | Completed

• 1 other identifier: KneeOAExercise-2
• Study Type: interventional
• Target: 44
• Locations: 1 country
• Sites: 1

Brief Summary

Knee Osteoarthritis (OA) is one of the most frequent causes of physical disability and pain among adults. Recent evidence suggests that shorter exercise programs that incorporate kinesthesia, balance and agility (KBA) techniques may result in more rapid symptom relief and functional improvements in comparison to traditional therapeutic exercise. KBA techniques are designed to improve dynamic joint stability by using a series of activities which challenge balance and coordination. To determine the independent effects of KBA training on functional abilities, it is necessary to test it as a training program unto itself. The proposed clinical trial is designed to do this by using three training groups: KBA only; lower extremity strength training only; and a combination of the two. The total exercise time and intensity of each condition will be approximately equal. A non-exercise group will control for any effects related to the testing procedures and the passage of time. Community volunteer men and women age 50 and over with physician diagnosed symptomatic knee OA will participate.

Conditions

Osteoarthritis

Keywords

Knee Osteoarthritis; arthritis

Outcome Measures

Primary Outcomes (1)

• (WOMAC) self assessment of physical function

  8 weeks

Study Arms (4)

1

EXPERIMENTAL

KBA exercise protocol

Other: KBA exercise

2

EXPERIMENTAL

strength training exercise protocol

Other: strength training exercise

3

EXPERIMENTAL

KBA and strength training protocol

Other: KBA and strength training

4

SHAM COMPARATOR

Other: Control group

Interventions

KBA exercise OTHER

KBA exercise protocol, 3 times per week for 8 weeks

1

strength training exercise OTHER

strength training exercise, 3 times per week for 8 weeks

2

KBA and strength training OTHER

KBA and strength training exercise, 3 times per week for 8 weeks

3

Control group OTHER

8 week control group

4

Eligibility Criteria

• Age: 50 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Aged 50 years or over of either gender
• Self-reported knee pain
• Physician diagnosed tibiofemoral OA, unilateral or bilateral, per ACR guidelines
• Demonstrated minimal knee OA related dysfunction per WOMAC score
• Not engaged in a regular leg exercise program for minimum of 6 months

You may not qualify if:

• High risk health status per (e.g.) ACSM guidelines
• Inability to obtain physician release for exercise
• Unresolved balance disorder
• Unresolved neurological disorder
• History of knee surgery or major knee trauma injury
• Hip or ankle instability, excessive weakness, surgery or major trauma injury
• Hip or knee replacement
• Intra-articular joint injection within 4 weeks of the study

Sponsors & Collaborators

• University of Zululand: lead

Study Sites (1)

University of Zululand

St. Petersburg, Florida, 33712, United States

Location

MeSH Terms

Conditions

Osteoarthritis; Osteoarthritis, Knee; Arthritis

Interventions

Resistance Training; Control Groups

Condition Hierarchy (Ancestors)

Joint Diseases; Musculoskeletal Diseases; Rheumatic Diseases

Intervention Hierarchy (Ancestors)

Exercise Therapy; Rehabilitation; Aftercare; Continuity of Patient Care; Patient Care; Therapeutics; Physical Therapy Modalities; Physical Conditioning, Human; Exercise; Motor Activity; Movement; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena; Epidemiologic Research Design; Epidemiologic Methods; Investigative Techniques; Research Design; Methods

Study Officials

• Matthew W Rogers, MS

  University of Zululand

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Doctoral Student, University of Zululand

Study Record Dates

• First Submitted: August 12, 2008
• First Posted: August 14, 2008
• Study Start: January 1, 2009
• Primary Completion: December 1, 2012
• Study Completion: December 1, 2012
• Last Updated: February 6, 2013

Record last verified: 2013-02

Locations

US (1)