Contrast Echocardiography in Patients With Pulmonary Arteriovenous Malformations (PAVMs)

NCT00733759 | Withdrawn

• 1 other identifier: IC/CLS10
• Study Type: observational
• Target: N/A
• Locations: 1 country
• Sites: 1

Brief Summary

Pulmonary arteriovenous malformations (PAVMs) are thin-walled abnormal vessels which provide direct capillary-free communications between the pulmonary and systemic circulations. Patients with PAVMs have usually have low blood oxygen levels and are at risk of other complications including strokes, brain abscesses, pregnancy-related complications and haemorrhage. We hypothesise that the complications of PAVM patients arise from their PAVMs and not the more recognised intracardiac forms of shunting. We propose to perform echocardiograms to enable assessment of the presence of other causes of capillary-free communications between the pulmonary and systemic circulations.

Conditions

Pulmonary Arteriovenous Malformations

Eligibility Criteria

• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients with pulmonary arteriovneous malformations

You may qualify if:

• patients with pulmonary arteriovenous malformations (PAVMs)

You may not qualify if:

• unable to provide informed consent

Sponsors & Collaborators

• Imperial College London: lead

Study Sites (1)

Imperial College Hammersmith Campus

London, W12 0NN, United Kingdom

Location

Study Officials

• Claire L Shovlin

  Imperial College London

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: August 12, 2008
• First Posted: August 13, 2008
• Study Start: February 1, 2004
• Primary Completion: March 1, 2008
• Study Completion: March 1, 2008
• Last Updated: October 9, 2019

Record last verified: 2019-10

Locations

GB (1)