NCT00731159

Brief Summary

Our aim is to evaluate the potential of a new laboratory method that measure sperm capacitation to predict fertilization of oocytes in patients that undergo IVF treatments

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
50

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started Jul 2008

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

July 1, 2008

Completed
1 month until next milestone

First Submitted

Initial submission to the registry

August 7, 2008

Completed
1 day until next milestone

First Posted

Study publicly available on registry

August 8, 2008

Completed
5 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 1, 2009

Completed
6 months until next milestone

Study Completion

Last participant's last visit for all outcomes

July 1, 2009

Completed
Last Updated

August 8, 2008

Status Verified

July 1, 2008

Enrollment Period

6 months

First QC Date

August 7, 2008

Last Update Submit

August 7, 2008

Conditions

Sperm Capacitation

Outcome Measures

Primary Outcomes (1)

  • Fertilization rate of human oocytes in thr "routine" IVF Laboratory work

    One year

Study Arms (1)

A

Sperm capacitation: Sperm capacitation is measured in a sample of the same ejaculated sperm unit given for fertilizing human oocytes in an IVF treatment cycle

Biological: sperm capacitationOther: biologicOther: sperm capacitation

Interventions

sperm capacitationBIOLOGICAL

sperm capacitation measured at Bar Ilan University

A
biologicOTHER

sperm synthesis of G-actine to F-actine

Also known as: sperm capacitation
A

Eligibility Criteria

Age18 Years - 40 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)
Sampling MethodNon-Probability Sample
Study Population

Patients requiring IVF within the "routine" work of an IVF Unit

You may qualify if:

  • Patients requiring IVF within the "routine" work of an IVF Unit
  • normo-responding woman
  • non ICSI cycles

You may not qualify if:

  • Patients undergoing ICSI only cycle
  • Low responders-less than 8 oocytes
  • Male patients with low semen volume

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Assaf Harofeh MC

Beer Yaacov, Zerifin, 70300, Israel

RECRUITING

MeSH Terms

Interventions

Sperm CapacitationBiological Products

Intervention Hierarchy (Ancestors)

FertilizationReproductionReproductive Physiological PhenomenaReproductive and Urinary Physiological PhenomenaComplex Mixtures

Central Study Contacts

arieh raziel, prof

CONTACT

97289779005araziel@asaf.health.gov.il

raphael ron-el, prof

CONTACT

97289779005rronel@asaf.health.gov.il

Study Design

Study Type
observational
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER GOV

Study Record Dates

First Submitted

August 7, 2008

First Posted

August 8, 2008

Study Start

July 1, 2008

Primary Completion

January 1, 2009

Study Completion

July 1, 2009

Last Updated

August 8, 2008

Record last verified: 2008-07

Locations

IL(1)